Results 171 to 180 of about 159,989 (316)

Apolipoprotein E3-mediated cellular uptake of reconstituted high-density lipoprotein bearing core 3, 10, or 17 nm hydrophobic gold nanoparticles

open access: yes, 2017
Skylar T Chuang, Young-Seok Shon, Vasanthy Narayanaswami Department of Chemistry and Biochemistry, California State University Long Beach, Long Beach, CA, USA Abstract: We have developed a high-density lipoprotein (HDL)-based platform for transport and
Chuang ST, Narayanaswami V, Shon YS
core  

Co‐ and Multi‐Pathologies in Parkinson's Disease: An International Parkinson and Movement Disorder Society Scientific Issues Committee Review

open access: yesMovement Disorders, EarlyView.
Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo   +10 more
wiley   +1 more source

<i>APOE4</i> Drives Sex- and Diet-Dependent Effects on AD-Like Pathology, Cognition, and Mitochondrial Function. [PDF]

open access: yesFASEB Bioadv
Johnson CN   +10 more
europepmc   +1 more source

Apolipoprotein A-I: Potential Protection Against Intestinal Injury Induced by Dietary Lipid

open access: yes
Jue-Xin Wang,1– 3,* Shi-Jia Yu,4,* Gang Huang,1,2 Yan-Bo Yu,1,2 Yan-Qing Li1,2 1Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong Province, 250012, People’s Republic of China; 2Laboratory of Translational ...
Yu SJ, Li YQ, Huang G, Yu YB, Wang JX
core  

Depletion of microglial compensation in glial network: Disease‐associated response dynamics in the revised amyloid hypothesis

open access: yesNeuroprotection, EarlyView.
The critical transition from amyloid pathology to irreversible neuronal loss in Alzheimer's disease hinges on the microglial response. This review aims to systematize the patterns of how microglia react within the glial context. Abstract Microglia mount coordinated, stage‐dependent compensatory programs in response to early amyloid β (Aβ) accumulation ...
Songtao Lei   +3 more
wiley   +1 more source

Neuroprotective effects of ursodeoxycholic acid in Parkinson's disease and Alzheimer's disease

open access: yesNeuroprotection, EarlyView.
In Parkinson's disease (PD) and Alzheimer's disease (AD), various shared pathological mechanisms exist. UDCA has been shown to exert neuroprotective effects in preclinical and clinical studies. Such effects include the mitigation of neuroinflammation as well as rescue effects on mitochondrial dysfunction, oxidative stress, impaired autophagy, and ...
Ashley En Yi Chong   +3 more
wiley   +1 more source

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