Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids
Movement Disorders, EarlyView.Abstract Neurodegenerative diseases are pathological states characterized by progressive alterations in brain homeostasis during aging. Synucleinopathies, including Parkinson's disease and dementia with Lewy bodies, are defined neuropathologically by the accumulation of inclusions known as Lewy bodies and Lewy neurites.
Manuel Flores‐León, Tiago F. Outeiro
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Jennifer G. Robinson +16 more
doaj +1 more source
Dysapolipoproteinaemia Influences the Relationship Between Very Low-Density Lipoprotein Cholesterol and Intra-Pancreatic Fat Deposition in Humans. [PDF]
NutrientsLiu Y +5 more
europepmc +1 more source
Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes [PDF]
, 1991 J.F. Diedrich +6 more
openalex +1 more source
CEST MRI Processing Pipeline in Pilot Study of Alzheimer's Disease Patients
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To develop a processing pipeline combining neuroimaging analysis tools with CEST postprocessing and utilize it in a pilot study probing differences between cognitively impaired (CI) Alzheimer's disease (AD) patients and cognitively normal (CN) individuals.
Alexander Asturias +6 more
wiley +1 more source
A longitudinal analysis of population-level lipid and apolipoprotein trends over two decades: descriptive assessment using patient medians in a Swedish tertiary care center. [PDF]
Lipids Health DisSejersen K, Larsson AO.
europepmc +1 more source
Formation of Spherical, Reconstituted High Density Lipoproteins Containing Both Apolipoproteins A-I and A-II Is Mediated by Lecithin:Cholesterol Acyltransferase [PDF]
, 2000 Moira A. Clay +3 more
openalex +1 more source
Liver Steatosis in Induced Hepatocytes From Carriers of Spinal Muscular Atrophy
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims Although classically characterized as a motor neuron disease, spinal muscular atrophy (SMA) is increasingly recognized as a multisystem disorder. We previously showed hepatocyte‐intrinsic steatosis in SMA, raising the question of whether SMA carriers, who are typically asymptomatic, may also exhibit subclinical hepatic ...
Lingyu Sun +15 more
wiley +1 more source
Association of tubular injury with lipid metabolism: A Mendelian randomization study. [PDF]
Medicine (Baltimore)Zhao K, Qian L, Ma X.
europepmc +1 more source
Apolipoproteins and Apolipoprotein Mimetic Peptides Modulate Phagocyte Trafficking through Chemotactic Activity [PDF]
, 2012 Jennifer H. Madenspacher +8 more
openalex +1 more source