Results 201 to 210 of about 126,178 (268)

Current and Emerging Pharmacological Therapies for Hypertriglyceridemia. [PDF]

Int J Mol Sci
Alhomoud IS.
europepmc   +1 more source

Human APOBEC3G suppresses homologous recombination and LIG4‐independent end joining in DNA double‐strand break repair

The FEBS Journal, EarlyView.
Chromosomal DNA double‐strand breaks (DSBs) are repaired by homologous recombination and nonhomologous end joining (NHEJ). Recent work has additionally established theta‐mediated end‐joining (TMEJ) as a mechanism for DSB joining. Cells lacking NHEJ and TMEJ can repair DSBs in a homology‐dependent manner.
Shinta Saito, Miori Murayama, Usaki Arai, Sekifumi Akatsu, Ami Yamamoto, Misaki Kadoguchi, Noritaka Adachi   +6 more
wiley   +1 more source

Box A of HMGB1 plasmid reverses the age-related changes in the plasma proteomic profile of perimenopausal monkeys. [PDF]

Sci Rep
Komkleow S, Jaroenporn S, Chokchaichamnankit D, Bubparam T, Yasom S, Ruangjaroon T, Svasti J, Ittiudomrak T, Sangvanich P, Mutirangura A, Srisomsap C.   +10 more
europepmc   +1 more source

Life‐stage variation in Sable Shearwater (Ardenna carneipes) physiology assessed using proteomics

Ibis, EarlyView.
Life‐stage transitions in seabirds involve substantial shifts in physiological demands, yet the molecular mechanisms underpinning these changes remain poorly resolved. Here we applied untargeted data‐independent acquisition mass spectrometry (DIA‐MS) to characterize and compare the plasma proteomes of fledgling and adult Sable Shearwaters Ardenna ...
Alix M. de Jersey, Alexander L. Bond, Richard Wilson, Graeme R. Zosky, Jack Rivers‐Auty, Jennifer L. Lavers   +5 more
wiley   +1 more source

Effects of apolipoprotein E and solute carrier organic anion transporter family member 1B1 gene polymorphisms on statin efficacy and safety in dyslipidemic patients. [PDF]

Pharmacogenet Genomics
Wu X, Cai Y, Su Y, Wei X, Nan T, Ye X, Lian S, Wei J.   +7 more
europepmc   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Age-related increase in plasma p-tau217 in amyloid-beta-negative cognitively unimpaired individuals affects diagnostic interpretation. [PDF]

Alzheimers Dement
Mammel AE, Gonzalez-Ortiz F, Mousavi A, Hallett K, Encarnacion M, Biehl D, Gill P, Ismael S, Fowler C, Doecke JD, Ward L, Frykman H.   +11 more
europepmc   +1 more source

HDL-mimetic peptide treatment reverses APOE4-induced transcriptomic and lipidomic alterations in the brain of humanized APOE mice. [PDF]

Alzheimers Dement
Chang A, Kim M, Glittenberg M, Qu W, Li D, Li L.   +5 more
europepmc   +1 more source

Plasmalogen deficiency and the Alzheimer's disease risk of apolipoprotein E4. [PDF]

Brain Commun
Hällqvist J, Taanman JW, Göteson A, Heywood WE, Schott JM, Hardy J, Landén M, Zetterberg H, Mills K, Ginsberg L.   +9 more
europepmc   +1 more source

Elevated Apolipoprotein B Is Associated With an Increased Risk of Adverse Outcomes in Aortic Stenosis. [PDF]

JACC Adv
Bansal A, Kapadia SR.
europepmc   +1 more source