Animal Models and Experimental Medicine, EarlyView.An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen +12 more
wiley +1 more source
The Relationship between Levels of Lipids and Lipoprotein B-100 in Maternal Serum and Umbilical Cord Serum and Assessing Their Effects on Newborn Infants Anthropometric Indices [PDF]
Journal of Midwifery & Reproductive Health, 2014 Background & aim: This study aimed to determine the relationship between lipid and apolipoprotein B-100 (apo B-100) levels in maternal and umbilical cord sera as well as the effects of these components on anthropometric measurements of newborn infants ...
Ashraf Ghiasi +2 more
doaj
Journal of Lipid Research, 1996 We have investigated the hypothesis that apolipoprotein B undergoes a regulated process of translocation into the endoplasmic reticulum (ER) which causes the protein to adopt a transmembrane configuration.
J M Leiper +4 more
doaj +1 more source
Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention
Animal Models and Experimental Medicine, EarlyView.This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie +4 more
wiley +1 more source
Apolipoprotein A-I, A-II, and VLDL-B-100 metabolism in men
Journal of Lipid Research, 2004 The impact of a low-fat diet and a high-MUFA diet on apolipoprotein A-I (apoA-I), apoA-II, and VLDL-apoB-100 metabolism in conditions of unrestricted (ad libitum) energy intake was compared in 65 men randomly assigned to one of two predefined ...
Sophie Desroches +7 more
doaj +1 more source
Apolipoprotein B-100-mediated motor neuron degeneration in sporadic amyotrophic lateral sclerosis. [PDF]
Brain Commun, 2022 Wong JK +9 more
europepmc +1 more source
Novel Techniques and Their Applications to Health Foods, Agricultural and Medical Biotechnology: Functional Genomics and Basic Epigenetic Controls in Plant and Animal Cells [PDF]
, 2004 Selected applications of novel techniques for analyzing Health Food formulations, as well as for advanced investigations in Agricultural and Medical Biotechnology aimed at defining the multiple connections between functional genomics and epigenomic ...
Baianu, I.C. +3 more
core
Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and Non-Hispanic Whites [PDF]
, 2009 BACKGROUND. Variations in gene allele frequencies can contribute to differences in the prevalence of some common complex diseases among populations. Natural selection modulates the balance in allele frequencies across populations.
Adiconis, Xian +9 more
core +3 more sources
Annals of Neurology, EarlyView.Objective Identifying modifiable factors influencing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) risk is important for prevention. Blood biomarkers, particularly cholesterol, have been associated with neurodegenerative risk, but findings in ALS are inconsistent, and data on FTD are limited.
Christos V. Chalitsios +5 more
wiley +1 more source
Receptor binding activity of lipid recombinants of apolipoprotein B-100 thrombolytic fragments.
Journal of Lipid Research, 1987 Apolipoprotein (apo) B-100, the protein constituent of low density lipoproteins (LDL), is the determinant responsible for LDL binding to the apoB,E(LDL) receptor on cells. The current study was designed to identify the region(s) of apoB-100 that interact
A Corsini +6 more
doaj +1 more source