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Interaction Between Maternal Obesity and Metabolic Dysfunction in Gestational Hypertension and Preeclampsia: A Prospective Birth Cohort Study. [PDF]
Chen J +11 more
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Real-world experience with lecanemab therapy for Alzheimer's disease in the Intermountain West. [PDF]
Curd BC +8 more
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Lipid Profile, Apolipoproteins, and Impulsivity in First Episode Mania. [PDF]
Behera R +4 more
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Familial defective apolipoprotein B-100: A review
Journal of Clinical Lipidology, 2016Familial defective apolipoprotein B-100 (FDB) is an autosomal dominant genetic disorder of lipid metabolism associated with hyperlipidemia and elevated risk for atherosclerosis. FDB is caused by mutations in APOB reducing the binding affinity between apolipoprotein B-100 and the low-density lipoprotein receptor.
Lars H. Andersen +3 more
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Genetic determinants of apolipoprotein B-100 kinetics
Current Opinion in Lipidology, 2010We review stable isotope tracer studies of apolipoprotein B-100 (apoB) kinetics concerning genetic polymorphisms and mutations that affect human lipoprotein metabolism.In obese men, the allelic combination of the apoB signal peptide, SP24, and cholesteryl ester transfer protein, CETP B1B1, is independently associated with lower VLDL apoB secretion ...
Theodore W K, Ng +4 more
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Arteriosclerosis, Thrombosis, and Vascular Biology, 1997
Abstract Apolipoprotein (apo) B-67 is a truncated form of apoB-100 due to deletion of an adenine at cDNA 9327. Heterozygotes have one allele making apoB-100; therefore, plasma apoB levels would be predicted to be at least 50% of normal. However, apoB-67 heterozygotes have total plasma apoB levels that are 24% of normal.
F K, Welty +5 more
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Abstract Apolipoprotein (apo) B-67 is a truncated form of apoB-100 due to deletion of an adenine at cDNA 9327. Heterozygotes have one allele making apoB-100; therefore, plasma apoB levels would be predicted to be at least 50% of normal. However, apoB-67 heterozygotes have total plasma apoB levels that are 24% of normal.
F K, Welty +5 more
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Apolipoprotein B synthesis in humans: Liver synthesizes only apolipoprotein B-100
Metabolism, 1985Apolipoprotein (apo) B-100 and B-48 are prominent apolipoproteins in VLDL, IDL, and chylomicrons. Organ cultures of normal adult human liver were established to ascertain the form of apo B synthesized by hepatocytes in humans. Human liver was minced and incubated in 15 mL methionine-free RPMI-1640 medium with 10% dialyzed fetal calf serum plus 250 ...
S B, Edge +3 more
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