Results 311 to 320 of about 145,356 (331)
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Apolipoprotein B-100 kinetics in visceral obesity: Associations with plasma apolipoprotein C-III concentration

Metabolism, 2002
Obesity is strongly associated with dyslipidemia, which may account for the associated increased risk of atherosclerosis and coronary disease. We aimed to test the hypothesis that kinetics of hepatic apolipoprotein B-100 (apoB) metabolism are disturbed in men with visceral obesity and to examine whether these kinetic defects are associated with ...
Dick C, Chan   +4 more
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Distribution of lipid-binding regions in human apolipoprotein B-100

Biochemistry, 1989
The distribution of lipid-binding regions of human apolipoprotein B-100 has been investigated by recombining proteolytic fragments of B-100 with lipids and characterizing the lipid-bound fragments by peptide mapping, amino acid sequencing, and immunoblotting.
G C, Chen   +8 more
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Structural comparison of human apolipoproteins B-48 and B-100

Biochemistry, 1987
In this study we have investigated the structural relationship between human apolipoproteins B-48 and B-100 by comparing protein structure and by comparing nucleotide sequence from intestinal and hepatic cDNA clones. Sequences from intestinal and hepatic cDNA were identical over the entire distance analyzed (7194 bases), which is more than required to ...
D A, Hardman   +9 more
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[11] Isolation and characterization of apolipoprotein B-100

1986
Publisher Summary Two physically separable macromolecules carry the designation apolipoproteinB. The long recognized form of apoB, large apoB or B-100, is the predominant protein in LDL and the major apoB protein found in human VLDL. This chapter describes the isolation and characterization of apolipoprotein B-100.
Waldo R. Fisher, Verne N. Schumaker
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Normotriglyceridemic Abetalipoproteinemia in Infancy: An Isolated Apolipoprotein B-100 Deficiency

Pediatrics, 1985
The plasma lipoproteins of a 1-year-old Japanese infant were studied because of malnutrition, severe decrease in plasma lipid level, and acanthocytosis. Plasma lipoprotein analysis revealed that low-density lipoproteins were deficient; however, low levels of triglyceride-rich lipoproteins were found in the plasma.
Y, Takashima   +8 more
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Structure-Function Relationships of Apolipoprotein B-100

1993
Apolipoprotein (apo) B-100 is a huge protein that has been difficult to study by traditional protein chemistry techniques. Other experimental approaches, such as investigations in cultured cells, and in human subjects with specific apoB mutations also have their limitations a novel approach using transgenic mice has yielded interesting information on ...
openaire   +1 more source

Haplotype analysis of apolipoprotein B-100 in subjects with familial defective apolipoprotein B-100

2002
Obiteljska pogreška u strukturi apolipoproteina B-100 je autosomno dodominantni premećaj zbog mutacije R3500Q gena za apolipoprotein B. Skupljeni su uzorci krvi 1489 ispitanika s hiperkolesterolemijom i/ili bolešću koronarnih arterija. Restrikcijskom izotipizacijom analiziran je ulomak DNA koji sadržava kodon 3500 gena za apo B.
openaire  

Familial defective apolipoprotein B-100 in Slovakia: are differences in prevalence of familial defective apolipoprotein B-100 explained by ethnicity?

Atherosclerosis, 2007
The objective of this study was to examine frequency of familial defective apo-B-100 (FDB, R3500Q mutation) in probands with the phenotype of familial hypercholesterolemia (FH) and in the general population of 40-year-old subjects in Slovakia and to characterize their lipid and clinical criteria and to compare the frequency of FDB with other ...
Juraj, Gasparovic   +5 more
openaire   +1 more source

Apolipoprotein B-100 Hopkins (arginine4019----tryptophan). A new apolipoprotein B-100 variant in a family with premature atherosclerosis and hyperapobetalipoproteinemia.

JAMA, 1989
A 43-year-old woman with severe coronary artery disease and hyperapobetalipoproteinemia was heterozygous for an abnormal Msp I apolipoprotein B (APOB) gene fragment because of the absence of the MspI site around codon 4046 in exon 29 of the APOB gene.
J A, Ladias   +7 more
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Familial defective apolipoprotein B-100 in Slovakia

Atherosclerosis, 2007
Juraj Gašparovič   +5 more
openaire   +1 more source

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