Results 341 to 350 of about 13,195,946 (379)
Some of the next articles are maybe not open access.
Clinica Chimica Acta, 2022
Elevated lipid levels during pregnancy have been shown to be related to the risk of preterm birth. Despite the importance of apolipoprotein (Apo) in lipid metabolism and transportation, evidence regarding apolipoprotein levels during pregnancy and preterm birth is still limited. Therefore, we aim to investigate the associations between maternal ApoA-1,
Qing, Liu +6 more
openaire +2 more sources
Elevated lipid levels during pregnancy have been shown to be related to the risk of preterm birth. Despite the importance of apolipoprotein (Apo) in lipid metabolism and transportation, evidence regarding apolipoprotein levels during pregnancy and preterm birth is still limited. Therefore, we aim to investigate the associations between maternal ApoA-1,
Qing, Liu +6 more
openaire +2 more sources
Structure and biosynthesis of apolipoprotein B
American Heart Journal, 1987Apolipoprotein (apo) B100 copy deoxyribonucleic acid (cDNA) has been cloned and sequenced. The total sequence of apo B100 messenger ribonucleic acid has been revealed by the work from our group, as well as other groups. The sequence spans 13,689 nucleotides from the initiation to the stop codon.
Margit Wettesten +7 more
openaire +3 more sources
Genetic abnormalities in apolipoprotein B
Trends in Cardiovascular Medicine, 1991Recent studies have demonstrated that mutations in the apolipoprotein (apo-) B gene can cause significant alterations in blood cholesterol levels. A variety of apo-B gene mutations that prevent the translation of a full-length apo-B molecule can lead to low blood cholesterol levels. A missense mutation in the apo-B gene has been described that prevents
Stephen G. Young, MacRae F. Linton
openaire +3 more sources
Apolipoprotein B and Lipoprotein Metabolism
1985Publisher Summary This chapter describes apolipoprotein B (apoB) and lipoprotein metabolism. ApoB-containing lipoproteins enter the circulation primarily as chylomicrons and very low-density lipoproteins (VLDL), but entry into other lipoprotein densities following secretion includes entry into intermediate density lipoprotein, low-density ...
Janet D. Sparks, Charles E. Sparks
openaire +3 more sources
Cerebrovascular Diseases, 2020
<b><i>Aim:</i></b> Prospective studies indicate that apolipoprotein (apo) measurements predict coronary heart disease risk. However, few population-based follow-up studies have addressed the predictive value of apo measurements in stroke risk.
San Lin You +5 more
openaire +2 more sources
<b><i>Aim:</i></b> Prospective studies indicate that apolipoprotein (apo) measurements predict coronary heart disease risk. However, few population-based follow-up studies have addressed the predictive value of apo measurements in stroke risk.
San Lin You +5 more
openaire +2 more sources
Apolipoprotein B synthesis in humans: Liver synthesizes only apolipoprotein B-100
Metabolism, 1985Apolipoprotein (apo) B-100 and B-48 are prominent apolipoproteins in VLDL, IDL, and chylomicrons. Organ cultures of normal adult human liver were established to ascertain the form of apo B synthesized by hepatocytes in humans. Human liver was minced and incubated in 15 mL methionine-free RPMI-1640 medium with 10% dialyzed fetal calf serum plus 250 ...
H.B. Brewer +3 more
openaire +3 more sources
Phosphorylation-dephosphorylation of apolipoprotein B
1986Publisher Summary There is little doubt of the physiologic importance of apolipoprotein B (apoB). In addition to being essential for the secretion of very low-density lipoprotein (VLDL), apoB plays a fundamental role in targeting cholesterol, as a component of LDL, to tissues via specific high-affinity receptors.
Roy A. Borchardt, Roger A. Davis
openaire +3 more sources
Rat apolipoprotein B differs in solubility properties from human apolipoprotein B
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1990Apolipoprotein B (ApoB) in general is known as an insoluble protein in aqueous buffers without the initial aid of denaturing agents. However, following the total delipidization of rat plasma low-density lipoproteins, a considerable portion (28.2 +/- 3.0%) of rat ApoB was found directly soluble in an aqueous buffer, N-ethylmorpholine acetate (pH 7.3) as
David L. Stiers +2 more
openaire +3 more sources
Apolipoprotein B, the villain in the drama?
European Journal of Pharmacology, 2015Low-density lipoprotein (LDL) is the major atherogenic lipoprotein and the primary target of lipid-lowering therapy for treating ischemic cardiovascular disease. Apolipoprotein B (apoB), an important structural component of LDL, plays a key role in cholesterol transport and removal in vascular wall.
Cang-Bao Xu, Qi Yu, Yaping Zhang
openaire +3 more sources
Apolipoprotein B intermediates [PDF]
Nature, 1992 Steven L. Chuck, VlSHWANATH R. LlNGAPPA
openaire +4 more sources