Results 31 to 40 of about 193,917 (194)

Familial defective apolipoprotein B-100: a mutation of apolipoprotein B that causes hypercholesterolemia.

Journal of Lipid Research, 1990
Familial defective apolipoprotein B-100 is a genetic disorder of apolipoprotein B-100 that causes moderate to severe hypercholesterolemia. A single amino acid mutation in apolipoprotein B diminishes the ability of low density lipoproteins to bind to the ...
TL Innerarity, RW Mahley, KH Weisgraber, TP Bersot, RM Krauss, GL Vega, SM Grundy, W Friedl, J Davignon, BJ McCarthy   +9 more
doaj   +1 more source

Estimating the level of carbamoylated plasma non-high-density lipoproteins using infrared spectroscopy [PDF]

, 2019
Background: The increased cardiovascular morbidity and mortality observed in chronic kidney disease (CKD) patients can be partly explained by the presence of carbamoylated lipoproteins. Lipid profiles can be determined with infrared spectroscopy. In this
De Baene, Linde, De Bruyne, Sander, Delanghe, Joris, Delanghe, Sigurd, Speeckaert, Marijn, Van Biesen, Wim   +5 more
core   +1 more source

Effects of inhibiting cholesterol absorption and synthesis on cholesterol and lipoprotein metabolism in hypercholesterolemic non-insulin-dependent diabetic men.

Journal of Lipid Research, 1996
Effectiveness of a simultaneous inhibition of cholesterol absorption and synthesis, caused by sitostanol ester margarine and pravastatin, was studied to control mild hypercholesterolemia in men with non-insulin-dependent diabetes mellitus (NIDDM) (n = 8).
H Gylling, T A Miettinen
doaj   +1 more source

Consensus document for lipid profile testing and reporting in Spanish clinical laboratories: what parameters should a basic lipid profile include?

Advances in Laboratory Medicine, 2023
Cardiovascular diseases (CVD) continue to be the main cause of death in our country. Adequate control of lipid metabolism disorders is a key challenge in cardiovascular prevention that is far from being achieved in real clinical practice.
Arrobas Velilla Teresa, Guijarro Carlos, Ruiz Raquel Campuzano, Piñero Manuel Rodríguez, Valderrama Marcos José Francisco, Pérez Pérez Antonio, Botana López Antonio M., López Ana Morais, García Donaire José Antonio, Obaya Juan Carlos, Castilla-Guerra Luis, Carratalá Vicente Pallares, Cabello Isabel Egocheaga, Lazo Mercedes Salgueira, Castellanos Rodrigo María Mar, Mostaza Prieto José María, Gómez Doblas Juan José, Buño Soto Antonio,   +18 more
doaj   +1 more source

Clinical significance of leptin in systemic lupus erythematosus

Современная ревматология, 2021
Objective: to study the frequency of hyperleptinemia in patients with systemic lupus erythematosus (SLE), its relationship with clinical and laboratory manifestations of the disease, drug therapy, and other metabolic disorders.Patients and methods.
L. V. Kondratyeva, T. A. Panafidina, T. V. Popkova, Yu. N. Gorbunova, M. V. Cherkasova   +4 more
doaj   +1 more source

The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]

, 2010
Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L., Mauldin, Kasuen, Oleszczuk, M., Ryan, R. O., Sykes, B. D.   +4 more
core   +2 more sources

Hubungan Kadar Apolipoprotein B Dengan Aterosklerosis Arteri Karotis Interna Pada Pasien Pasca Stroke Iskemik [PDF]

, 2011
Background: Ischemic stroke is caused by brain artery obstruction or narrowing called atherosclerosis. Its marker is the thickness of tunica intima-media (intima-media thickness / IMT) of the artery. Apolipoprotein B is the indicator of atherosclerosis
Teguh, Haryo
core  

The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise [PDF]

, 2016
© 2016 The Author(s) Purpose: The Oral Fat Tolerance Test (OFTT) is regarded as a repeatable measure used to assess postprandial triglyceride (TAG) levels, with higher levels observed in cardio-metabolic disorders.
Carroll, S., Ingle, L., O’Doherty, A. F., Rigby, A. S., Sathyapalan, T.   +4 more
core   +1 more source

Low rates of apoB secretion from HepG2 cells result from reduced delivery of newly synthesized triglyceride to a “secretion-coupled” pool.

Journal of Lipid Research, 1996
The present study was aimed at defining the roles of intracellular triglyceride pools in apolipoprotein B secretion from HepG2 cells. Oleic acid (0.2 mmol/L) in the medium stimulated both triglyceride synthesis and apolipoprotein B secretion. Stimulation
X Wu, A Shang, H Jiang, H N Ginsberg
doaj   +1 more source

Lumican silencing ameliorates β-glycerophosphate-mediated vascular smooth muscle cell calcification by attenuating the inhibition of APOB on KIF2C activity

Open Medicine, 2023
Adverse cardiovascular events are associated with vascular calcification (VC) process, where vascular smooth muscle cells (VSMCs) differentiate into osteoblastic phenotype and deposit hydroxyapatite crystals. Microtubule-associated protein kinesin family
Li Haibin, Zhang Chunyan, Liu Qiang
doaj   +1 more source