Results 31 to 40 of about 467,300 (362)
A Study of Serum Apolipoprotein A1, Apolipoprotein B and Lipid Profile in Stroke [PDF]
Background: Role of Serum Lipids, Lipoproteins and Lipoprotein related variables in the prediction of Stroke is less clear. Abnormalities in plasma Lipoproteins are the most firmly established and best understood risk factors for Atherosclerosis and ...
Shilpasree AS+3 more
doaj +1 more source
Clinical significance of leptin in systemic lupus erythematosus
Objective: to study the frequency of hyperleptinemia in patients with systemic lupus erythematosus (SLE), its relationship with clinical and laboratory manifestations of the disease, drug therapy, and other metabolic disorders.Patients and methods.
L. V. Kondratyeva+4 more
doaj +1 more source
Molecular Dynamics Simulation of Apolipoprotein E3 Lipid Nanodiscs [PDF]
Nanodiscs are binary discoidal complexes of a phospholipid bilayer circumscribed by belt-like helical scaffold proteins. Using coarse-grained and all-atom molecular dynamics simulations, we explore the stability, size, and structure of nanodiscs formed between the N-terminal domain of apolipoprotein E3 (apoE3-NT) and variable number of 1,2-dimyristoyl ...
arxiv
Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders. [PDF]
Apolipoprotein (apo) E was initially described as a lipid transport protein and major ligand for low density lipoprotein (LDL) receptors with a role in cholesterol metabolism and cardiovascular disease.
Mahley, Robert W
core +1 more source
Publisher Summary The methods discussed in this chapter provide fairly simple, sensitive, and reliable means of determining the content of apoB-48 and apoB-100 in Sf>12 lipoproteins, by analytical sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), with subsequent conventional protein staining and gel scanning.
Karpe, F+3 more
openaire +4 more sources
The secondary structure of apolipoprotein A-I on 9.6-nm reconstituted high-density lipoprotein determined by EPR spectroscopy. [PDF]
Apolipoprotein A-I (ApoA-I) is the major protein component of high-density lipoprotein (HDL), and is critical for maintenance of cholesterol homeostasis.
Borja, Mark S+5 more
core +1 more source
Background: Psoriasis has been linked to dyslipidemia. However, the magnitude of the association between psoriasis and serum apolipoproteins A1 and B remains unclear.
Fang Wang+6 more
doaj
Cardiovascular diseases (CVD) continue to be the main cause of death in our country. Adequate control of lipid metabolism disorders is a key challenge in cardiovascular prevention that is far from being achieved in real clinical practice.
Arrobas Velilla Teresa+18 more
doaj +1 more source
Endothelial Cell-specific Loss of Breast Cancer Susceptibility Gene 2 Exacerbates Atherosclerosis [PDF]
The BReast CAncer type 2 susceptibility protein (BRCA2) responds to DNA damage by participating in homology-directed repair. BRCA2 deficiency culminates in defective DNA damage repair (DDR) that when prolonged leads to the accumulation of DNA damage causing cancer or apoptosis.
arxiv
Adverse cardiovascular events are associated with vascular calcification (VC) process, where vascular smooth muscle cells (VSMCs) differentiate into osteoblastic phenotype and deposit hydroxyapatite crystals. Microtubule-associated protein kinesin family
Li Haibin, Zhang Chunyan, Liu Qiang
doaj +1 more source