Results 101 to 110 of about 73,331 (301)
Journal of Lipid Research, 1988 Apolipoprotein (apo) C-II deficiency is characterized by elevated plasma triglycerides, chylomicrons, and very low density lipoproteins, as well as reduced levels of low density and high density lipoproteins.
D L Sprecher +6 more
doaj +1 more source
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Annals of Neurology, EarlyView.Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
Specificity of the lipid-binding domain of apoC-II for the substrates and products of lipolysis
Journal of Lipid Research, 2001 Functional similarities between colipase and apolipoprotein C-II (apoC-II) in activating lipases suggest that apoC-II may, like colipase, preferentially interact with interfaces containing the substrates and products of lipolysis. To test this hypothesis,
M. Dahim +3 more
doaj +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
A Novel APOC2 Mutation in a Colombian Patient with Recurrent Hypertriglyceridemic Pancreatitis
The Application of Clinical Genetics, 2020 Gabriel D Pinilla-Monsalve,1,* Juliana Lores,1,2,* Harry Pachajoa,1,2 Juan D López-Ponce de León,1,3 Alejandro López,1,4 Lisa X Rodríguez-Rojas,1,2 José A Nastasi-Catanese1,2 1Faculty of Health Sciences, Universidad ...
Pinilla-Monsalve GD +6 more
doaj
Gut and Liver, 2018 Background/AimsChanges in lipid profiles in patients infected with hepatitis C virus (HCV) during direct-acting antiviral therapy have been reported in recent years.
Takeshi Chida +10 more
doaj +1 more source
Association of the lipoprotein lipase and Apolipoprotein C-II gene polymorphisms with risk of dyslipidemia in smokers and non-smokers male. [PDF]
Indian Heart J, 2022 Al-Samawi RI, Smaism MF.
europepmc +1 more source
Apolipoprotein C-II Modifications Associated with an Infusion of Artificial Lipid Particles
, 1988 Artificial lipid particles used as parenteral nutrition solution do not contain any apolipoproteins when they are infused into the circulation. Despite the absence of apolipoproteins, the metabolism of artificial lipid particles is similar to that of ...
Tonouchi, Hitoshi +6 more
core +1 more source
Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
Journal of Lipid Research, 2000 Familial combined hyperlipidemia (FCHL) is a common inherited hyperlipidemia and a major risk factor for atherothrombotic cardiovascular disease. The cause(s) leading to FCHL are largely unknown, but the existence of unidentified “major” genes that would
Joan Carles Escolà-Gil +5 more
doaj +1 more source