Results 171 to 180 of about 73,331 (301)

Time‐Restricted Eating Promotes Weight Loss and Favorable Changes in Adipose in Obesity: The TREAD Randomized Control Trial

Obesity, EarlyView.
ABSTRACT Objective Examine time‐restricted eating (TRE) as a strategy to promote weight loss and cardiometabolic health in adults with obesity. Methods TRE in obesity and ADipose Tissue (TREAD) was a single‐center 12‐week RCT, involving 1:1 randomization to 10‐h TRE versus standard of care (SOC) in adults with obesity (BMI 30–50 kg/m2) without diabetes
Michael J. Wilkinson, Erika Padilla, Yuqi Wang, Sawye Raygani, Emily N. C. Manoogian, Kyla Laing, Khang Tong, Lin Liu, David Van, Justina Nguyen, Alan R. Saltiel, Shannon M. Reilly, Monica O'Neal, Satchidananda Panda, Amit R. Majithia, Pam R. Taub   +15 more
wiley   +1 more source

Creation of Apolipoprotein C-II (ApoC-II) Mutant Mice and Correction of Their Hypertriglyceridemia with an ApoC-II Mimetic Peptide. [PDF]

J Pharmacol Exp Ther, 2016
Sakurai T, Sakurai A, Vaisman BL, Amar MJ, Liu C, Gordon SM, Drake SK, Pryor M, Sampson ML, Yang L, Freeman LA, Remaley AT.   +11 more
europepmc   +1 more source

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

PROTEOMICS, EarlyView.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà, Loredana Leggio, Greta Paternò, Elena Giusto, Laura Civiero, Vincenzo Cunsolo, Silvia Vivarelli, Antonella Di Francesco, Emanuele Alpi, Nunzio Iraci, Rosaria Saletti   +10 more
wiley   +1 more source

Preclinical Evaluation of Berry Extracts as a Nutritional Intervention to Alleviate Myocardial Ischemia–Reperfusion Injury and Atherosclerosis Development

Phytotherapy Research, EarlyView.
Schematic representation of the experimental design and the proposed mechanisms underlying the cardioprotective and anti‐atherosclerotic effects of Greek‐derived berry extracts. C57BL/6 mice with WD–induced MS and ApoE−/− mice with atherosclerosis received chronic supplementation with WMex or BBex.
Lydia Symeonidi, Panagiota‐Efstathia Nikolaou, Panagiotis Stathopoulos, Andriana Christodoulou, Alexandra Svouraki, Panagiotis Efentakis, Christina Chania, Angeliki Choustoulaki, Maria Xenaki, Anna Agapaki, Maria Tsoumani, Nikolaos Kostomitsopoulos, Ioulia Tseti, Gemma Vilahur, Alexios‐Leandros Skaltsounis, Ioanna Andreadou   +15 more
wiley   +1 more source

Proteomic and metabolic signatures of female reproductive factors and risk of age‐related ocular diseases: A large prospective cohort study

VIEW, EarlyView.
The full editable vector source file of this graphical abstract is uploaded as a supplementary EPS file for typesetting. All elements are copyright‐free. Abstract Age‐related ocular diseases (ARODs), including cataract, primary open‐angle glaucoma (POAG), and age‐related macular degeneration (AMD), are leading causes of vision impairment and exhibit ...
Linge Jian, Zhiqian Huang, Keke Zhang, Jing Lin, Jia You, Yi Lu, Xiangjia Zhu   +6 more
wiley   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source

Effects of Pemafibrate on Cardio-Ankle Vascular Index (CAVI) in Patients with Type 2 Diabetes or Ischemic Heart Disease: A 24-Week Observational Study

Vascular Health and Risk Management
Yasuhiro Watanabe,1 Shoya Nonaka,2 Shuhei Yamaoka,1 Shoko Nakamura,1 Osamu Horikawa,1 Takashi Yamaguchi,1 Shuji Sato,2 Shunsuke Todani,2 Yuta Sugizaki,2 Takuro Ito,2 Hiroshi Mikamo,2 Mao Takahashi,2 Daiji Nagayama,3 Kazuhiro Shimizu,1 Atsuhito Saiki1 ...
Watanabe Y, Nonaka S, Yamaoka S, Nakamura S, Horikawa O, Yamaguchi T, Sato S, Todani S, Sugizaki Y, Ito T, Mikamo H, Takahashi M, Nagayama D, Shimizu K, Saiki A   +14 more
doaj  

Differential Roles for IL‐4Rα and IL‐13Rα1 in Immune Cell Infiltration and Epithelial Remodeling in Experimental Eosinophilic Gastritis

Allergy, EarlyView.
This study described the development of an experimental model for eosinophilic gastritis (EoG). Experimental EoG recapitulates histopathological features of human disease. including foveolar elongation, fibrosis, eosinophilia, mastocytosis and shared transcriptional programs.
Anish Dsilva, Shraddha Sharma, Shireen Barakey, Ariel Wagner, Alice Keisar, Tali Bar‐on, Michal Itan, Ariel Munitz   +7 more
wiley   +1 more source

A comparison of sequential density ultracentrifugation and density gradient ultracentrifugation for the proteomic analysis of high-density lipoprotein. [PDF]

Front Cardiovasc Med
Beazer JD, Ljunggren S, Karlsson H, Davies IG, Freeman DJ.   +4 more
europepmc   +1 more source

Challenging the prokaryotic MGE‐defense origin of eukaryotic RNA editing

mLife, EarlyView.
Yuange Duan, Qiuhua Xie, Jiajia Yang, Wanzhi Cai, Hu Li   +4 more
wiley   +1 more source