Results 21 to 30 of about 55,604 (311)
On the Aggregation of Apolipoprotein A-I
International Journal of Molecular Sciences, 2022 In vivo, apolipoprotein A-I (ApoA-I) is commonly found together with lipids in so-called lipoprotein particles. The protein has also been associated with several diseases—such as atherosclerosis and amyloidosis—where insoluble aggregates containing ApoA-I are deposited in various organs or arteries.
Rebecca Frankel, Emma Sparr, Sara Linse
openaire +2 more sources
Aqueous Humor Apolipoprotein Concentration and Severity of Diabetic Retinopathy in Type 2 Diabetes
Mediators of Inflammation, 2022 An imbalance of plasma apolipoproteins has been linked to diabetic retinopathy (DR); however, there is scarce information regarding their presence in the aqueous humor (AH) and their role in DR.
Lucia Saucedo +4 more
doaj +1 more source
Apolipoprotein[a] is not associated with apolipoprotein B in human liver
Journal of Lipid Research, 1994 The aim of this research was to determine whether apolipoprotein[a] (apo[a]) is linked to apolipoprotein B (apoB) in human liver. Four ELISAs were developed: 1) a competition assay that measures apoB; 2) a competition assay that measures apo[a]; 3) a capture assay based on capture of apo[a] by a polyclonal antibody and detection of co-immobilized apoB ...
Lisa H. Munro +2 more
openaire +3 more sources
The role of APOBEC3-induced mutations in the differential evolution of monkeypox virus [PDF]
arXiv, 2023 Recent studies show that newly sampled monkeypox virus (MPXV) genomes exhibit mutations consistent with Apolipoprotein B mRNA Editing Catalytic Polypeptide-like3 (APOBEC3)-mediated editing, compared to MPXV genomes collected earlier. It is unclear whether these single nucleotide polymorphisms (SNPs) result from APOBEC3-induced editing or are a ...
arxiv
Smoking and apolipoprotein levels: A meta-analysis of published data
Toxicology Reports, 2022 Background: Apolipoproteins are major components of lipoproteins such as high-density lipoprotein (HDL) and very-low-density lipoprotein and are considered nontraditional markers in the risk assessment for cardiovascular disease.
Alba Romero Kauss +6 more
doaj
Protein corona critically affects the bio-behaviors of SARS-CoV-2 [PDF]
arXiv, 2021 The outbreak of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a worldwide public health crisis. When the SARS-CoV-2 enters the biological fluids in the human body, different types of biomolecules (in particular proteins) may adsorb on its surface and alter its infection ability.
arxiv
Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]
arXiv, 2022 Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
PLoS Pathogens, 2014 Apolipoprotein B (ApoB) and ApoE have been shown to participate in the particle formation and the tissue tropism of hepatitis C virus (HCV), but their precise roles remain uncertain.
Takasuke Fukuhara +13 more
doaj +1 more source
Alzheimer Disease is Associated with Isotropic Ocular Enlargement [PDF]
arXiv, 2023 Recent studies have documented ocular changes in dementia patients, especially Alzheimer Disease (AD). In this study, we explored the change of eye size and eye shape in dementia, including AD patients. The eyeball volume and diameters were estimated via T1-weighted brain magnetic resonance (MR) images in the OASIS-3 database which included 83 AD, 247 ...
arxiv