Results 11 to 20 of about 26,040 (266)

Apolipoproteins of high, low, and very low density lipoproteins in human bile

Journal of Lipid Research, 1983
We tested the hypothesis that apolipoproteins, the protein constituents of plasma lipoproteins, are secreted into bile. We examined human gallbladder bile obtained at surgery (N = 54) from subjects with (N = 44) and without (N = 10) gallstones and ...
R B Sewell, S J Mao, T Kawamoto, N F LaRusso   +3 more
doaj   +1 more source

ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions

Journal of Lipid Research, 2003
ATP binding cassette transporter A1 (ABCA1) mediates the transport of phospholipids and cholesterol from cells to lipid-poor HDL apolipoproteins. Cholesterol loading of cells induces ABCA1, implicating cholesterol as its major physiologic substrate.
Ashley M. Vaughan, John F. Oram
doaj   +1 more source

Apolipoprotein M [PDF]

Lipids in Health and Disease, 2004
AbstractApolipoprotein M (apoM) is a 26-kDa protein that is mainly associated with high-density lipoprotein (HDL) in human plasma, with a small proportion present in triglyceride-rich lipoproteins (TGRLP) and low-density lipoproteins (LDL). Human apoM gene is located in p21.31 on chromosome 6 (chromosome 17, in mouse).
Nilsson-Ehle Peter, Zhang Xiaoying, Luo Guanghua, Xu Ning   +3 more
openaire   +3 more sources

The amphipathic helix in the exchangeable apolipoproteins: a review of secondary structure and function.

Journal of Lipid Research, 1992
Site-directed mutagenesis and other molecular biology-based techniques are now available for probing the amphipathic alpha helix structural motif in the exchangeable apolipoproteins. Here we survey the published literature on lipid-binding and functional
JP Segrest, MK Jones, H De Loof, CG Brouillette, YV Venkatachalapathi, GM Anantharamaiah   +5 more
doaj   +1 more source

The effect of apolipoprotein(a)-, apolipoprotein E-, and apolipoprotein A4- polymorphisms on quantitative lipoprotein(a) concentrations [PDF]

Twin Research, 2000
AbstractThe effects of apolipoprotein (a), apolipoprotein-E, and apolipoprotein-A4 isoforms on quantitative lipoprotein(a) [Lp(a)] levels were assessed in a sample of 142 Dutch families consisting of two parents and their adolescent twin offspring. A total heritability of 95% was estimated for plasma Lp(a) concentrations.
Boomsma, D. I., Knijff, P., Kaptein, A., Labeur, C., Martin, N. G., Havekes, L. M., Princen, H. M.   +6 more
openaire   +5 more sources

Simultaneous LC/MS/MS quantification of eight apolipoproteins in normal and hypercholesterolemic mouse plasma[S]

Journal of Lipid Research, 2019
Apolipoproteins are major structural and functional constituents of lipoprotein particles. As modulators of lipid metabolism, adipose tissue biology, and energy homeostasis, apolipoproteins may serve as biomarkers or potential therapeutic targets for ...
Richard Wagner, Julia Dittrich, Joachim Thiery, Uta Ceglarek, Ralph Burkhardt   +4 more
doaj   +1 more source

Plasma lipoproteins: apolipoprotein structure and function.

Journal of Lipid Research, 1984
Plasma lipoprotein metabolism is regulated and controlled by the specific apolipoprotein (apo-) constituents of the various lipoprotein classes. The major apolipoproteins include apoE, apoB, apoA-I, apoA-II, apoA-IV, apoC-I, apoC-II, and apoC-III ...
R W Mahley, T L Innerarity, S C Rall, Jr, K H Weisgraber   +3 more
doaj   +1 more source

Multidimensional profiling of plasma lipoproteins by size exclusion chromatography followed by reverse-phase protein arrays

Journal of Lipid Research, 2011
The composition of lipoproteins and the association of proteins with various particles are of much interest in the context of cardiovascular disease. Here, we describe a technique for the multidimensional analysis of lipoproteins and their associated ...
Gregor Dernick, Stefan Obermüller, Cyrill Mangold, Christine Magg, Hugues Matile, Oliver Gutmann, Elisabeth von der Mark, Corinne Handschin, Cyrille Maugeais, Eric J. Niesor   +9 more
doaj   +1 more source

Reconfiguring Nature’s Cholesterol Accepting Lipoproteins as Nanoparticle Platforms for Transport and Delivery of Therapeutic and Imaging Agents

Nanomaterials, 2020
Apolipoproteins are critical structural and functional components of lipoproteins, which are large supramolecular assemblies composed predominantly of lipids and proteins, and other biomolecules such as nucleic acids.
Skylar T. Chuang, Siobanth Cruz, Vasanthy Narayanaswami   +2 more
doaj   +1 more source

An MRM-Based Multiplexed Quantification Assay for Human Adipokines and Apolipoproteins

Molecules, 2020
Adipokines and apolipoproteins are key regulators and potential biomarkers in obesity and associated diseases and their quantitative assessment is crucial for functional analyses to understand disease mechanisms.
Laura Krieg, Alexandra Schaffert, Matthias Kern, Kathrin Landgraf, Martin Wabitsch, Annette G. Beck-Sickinger, Antje Körner, Matthias Blüher, Martin von Bergen, Kristin Schubert   +9 more
doaj   +1 more source