Results 11 to 20 of about 25,763 (118)

The amphipathic helix in the exchangeable apolipoproteins: a review of secondary structure and function.

Journal of Lipid Research, 1992
Site-directed mutagenesis and other molecular biology-based techniques are now available for probing the amphipathic alpha helix structural motif in the exchangeable apolipoproteins. Here we survey the published literature on lipid-binding and functional
JP Segrest, MK Jones, H De Loof, CG Brouillette, YV Venkatachalapathi, GM Anantharamaiah   +5 more
doaj   +1 more source

Simultaneous LC/MS/MS quantification of eight apolipoproteins in normal and hypercholesterolemic mouse plasma[S]

Journal of Lipid Research, 2019
Apolipoproteins are major structural and functional constituents of lipoprotein particles. As modulators of lipid metabolism, adipose tissue biology, and energy homeostasis, apolipoproteins may serve as biomarkers or potential therapeutic targets for ...
Richard Wagner, Julia Dittrich, Joachim Thiery, Uta Ceglarek, Ralph Burkhardt   +4 more
doaj   +1 more source

Apolipoproteins and cancer

Cancer Medicine, 2019
The role of apolipoproteins in cardiovascular disease has been well investigated, but their participation in cancer has only been explored in a few published studies which showed a close link with certain kinds of cancer.
Liwen Ren, Jie Yi, Wan Li, Xiangjin Zheng, Jinyi Liu, Jinhua Wang, Guanhua Du   +6 more
doaj   +1 more source

Plasma lipoproteins: apolipoprotein structure and function.

Journal of Lipid Research, 1984
Plasma lipoprotein metabolism is regulated and controlled by the specific apolipoprotein (apo-) constituents of the various lipoprotein classes. The major apolipoproteins include apoE, apoB, apoA-I, apoA-II, apoA-IV, apoC-I, apoC-II, and apoC-III ...
R W Mahley, T L Innerarity, S C Rall, Jr, K H Weisgraber   +3 more
doaj   +1 more source

Multidimensional profiling of plasma lipoproteins by size exclusion chromatography followed by reverse-phase protein arrays

Journal of Lipid Research, 2011
The composition of lipoproteins and the association of proteins with various particles are of much interest in the context of cardiovascular disease. Here, we describe a technique for the multidimensional analysis of lipoproteins and their associated ...
Gregor Dernick, Stefan Obermüller, Cyrill Mangold, Christine Magg, Hugues Matile, Oliver Gutmann, Elisabeth von der Mark, Corinne Handschin, Cyrille Maugeais, Eric J. Niesor   +9 more
doaj   +1 more source

Reconfiguring Nature’s Cholesterol Accepting Lipoproteins as Nanoparticle Platforms for Transport and Delivery of Therapeutic and Imaging Agents

Nanomaterials, 2020
Apolipoproteins are critical structural and functional components of lipoproteins, which are large supramolecular assemblies composed predominantly of lipids and proteins, and other biomolecules such as nucleic acids.
Skylar T. Chuang, Siobanth Cruz, Vasanthy Narayanaswami   +2 more
doaj   +1 more source

Cholesterols, Apolipoproteins, and Their Associations with the Presence and Severity of Diabetic Retinopathy: A Systematic Review

Vision, 2022
Serum apolipoproteins have been reported as a more significant marker for diabetic retinopathy (DR) compared with serum cholesterols. This article aims to review the associations between serum cholesterols and apolipoproteins, and the presence and ...
Soefiandi Soedarman, King Hans Kurnia, Alberthus Donni Budi Prasetya, Muhammad Bayu Sasongko   +3 more
doaj   +1 more source

An MRM-Based Multiplexed Quantification Assay for Human Adipokines and Apolipoproteins

Molecules, 2020
Adipokines and apolipoproteins are key regulators and potential biomarkers in obesity and associated diseases and their quantitative assessment is crucial for functional analyses to understand disease mechanisms.
Laura Krieg, Alexandra Schaffert, Matthias Kern, Kathrin Landgraf, Martin Wabitsch, Annette G. Beck-Sickinger, Antje Körner, Matthias Blüher, Martin von Bergen, Kristin Schubert   +9 more
doaj   +1 more source

Mass Spectrometry for the Monitoring of Lipoprotein Oxidations by Myeloperoxidase in Cardiovascular Diseases

Molecules, 2021
Oxidative modifications of HDLs and LDLs by myeloperoxidase (MPO) are regularly mentioned in the context of atherosclerosis. The enzyme adsorbs on protein moieties and locally produces oxidizing agents to modify specific residues on apolipoproteins A-1 ...
Catherine Coremans, Cédric Delporte, Frédéric Cotton, Phillipe Van De Borne, Karim Zouaoui Boudjeltia, Pierre Van Antwerpen   +5 more
doaj   +1 more source

Apolipoprotein E allelic influence on human cerebrospinal fluid apolipoproteins

Journal of Lipid Research, 1998
The major apolipoproteins (apo) on human cerebrospinal fluid lipoproteins are apoA-I and apoE. Given the association between inheritance of the ε4 allele of the apoE gene (APOE4) and increased susceptibility to Alzheimer's disease, we tested the ...
Kathleen S. Montine, Casey N. Bassett, Joyce J. Ou, William R. Markesbery, Larry L. Swift, Thomas J. Montine   +5 more
doaj   +1 more source