Results 1 to 10 of about 126,178 (268)

Expression of the human apoE2 isoform in adipocytes: altered cellular processing and impaired adipocyte lipogenesis

Journal of Lipid Research, 2011
Expression of apoE in adipocytes has been shown to have an important role in modulating adipocyte triglyceride (TG) metabolism and gene expression that is independent of circulating and extracellular apoE.
Zhi H. Huang, Nobuyo Maeda, Theodore Mazzone   +2 more
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Research advances of correlation between apolipoprotein C3 and diabetes mellitus and diabetic kidney disease

Linchuang shenzangbing zazhi
Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycemia due to multiple etiological factors. In diabetics, lipid accumulation may cause lipid peroxidation and cell membrane lipid oxidation, leading to cellular injuries and ...
Ling-zhi Li, Xiao-yi Cai, Qi-jun Wan, Xiu-li Zhang   +3 more
doaj   +1 more source

ApoA5 knockdown improves whole-body insulin sensitivity in high-fat-fed mice by reducing ectopic lipid content

Journal of Lipid Research, 2015
ApoA5 has a critical role in the regulation of plasma TG concentrations. In order to determine whether ApoA5 also impacts ectopic lipid deposition in liver and skeletal muscle, as well as tissue insulin sensitivity, we treated mice with an antisense ...
João Paulo G. Camporez, Shoichi Kanda, Max C. Petersen, François R. Jornayvaz, Varman T. Samuel, Sanjay Bhanot, Kitt Falk Petersen, Michael J. Jurczak, Gerald I. Shulman   +8 more
doaj   +1 more source

Serum lipid metabolism in psoriasis and psoriatic arthritis – an update

Archives of Medical Science, 2019
Introduction Psoriasis and psoriatic arthritis (PSA) are chronic, inflammatory, systemic diseases characterized by metabolic abnormalities, including an increased cardiovascular risk and an oxidative imbalance.
Aldona Pietrzak, Paweł Chabros, Ewelina Grywalska, Paweł Kiciński, Kinga Franciszkiewicz-Pietrzak, Dorota Krasowska, Grzegorz Kandzierski   +6 more
doaj   +1 more source

Lipoprotein(a), a Lethal Player in Calcific Aortic Valve Disease

Frontiers in Cell and Developmental Biology, 2022
Calcified aortic valve disease (CAVD) is the most common valvular cardiovascular disease with increasing incidence and mortality. The primary treatment for CAVD is surgical or transcatheter aortic valve replacement and there remains a lack of effective ...
Jiahui Hu, Jiahui Hu, Jiahui Hu, Jiahui Hu, Hao Lei, Hao Lei, Hao Lei, Hao Lei, Leiling Liu, Leiling Liu, Leiling Liu, Leiling Liu, Danyan Xu, Danyan Xu, Danyan Xu, Danyan Xu   +15 more
doaj   +1 more source

Lipid monolayers: interactions with the apoprotein of high density plasma lipoprotein

Journal of Lipid Research, 1968
Monolayer techniques were used to study the interactions of various lipids (cholesterol, lysophosphatidyl choline, phosphatidal ethanolamine, phosphatidyl choline, sphingomyelin, stearic acid, and lipids extracted from plasma high density lipoproteins ...
German Camejo, Giuseppe Colacicco, Maurice M. Rapport   +2 more
doaj   +1 more source

Acute exposure to apolipoprotein A1 inhibits macrophage chemotaxis in vitro and monocyte recruitment in vivo

eLife, 2016
Apolipoprotein A1 (apoA1) is the major protein component of high-density lipoprotein (HDL) and has well documented anti-inflammatory properties. To better understand the cellular and molecular basis of the anti-inflammatory actions of apoA1, we explored ...
Asif J Iqbal, Tessa J Barrett, Lewis Taylor, Eileen McNeill, Arun Manmadhan, Carlota Recio, Alfredo Carmineri, Maximillian H Brodermann, Gemma E White, Dianne Cooper, Joseph A DiDonato, Maryam Zamanian-Daryoush, Stanley L Hazen, Keith M Channon, David R Greaves, Edward A Fisher   +15 more
doaj   +1 more source

Association between heart rate variability and apolipoprotein B/ apolipoprotein A1 ratio in patients with diabetic kidney disease stratified by estimated glomerular filtration rate

Zhongguo linchuang yanjiu
Objective To investigate the stratified correlation between heart rate variability（HRV）and the apolipoprotein B/apolipoprotein A1（ApoB/ApoA1）ratio in patients with diabetic kidney disease（DKD）across different levels of estimated glomerular filtration ...
YAN Wenyan, YANG Juan, BAI Mingchuan, JIANG Luyue   +3 more
doaj   +1 more source

The Influence of Body Fat and Lean Mass on HbA1c and Lipid Profile in Children and Adolescents with Type 1 Diabetes Mellitus

Diseases, 2023
Glycated hemoglobin (HbA1c) is used to assess glycemic control in Type 1 diabetes (DM1) patients. Apolipoproteins play an essential role in DM1 pathophysiology and may be associated with complications and HbA1c.
Thais Menegucci, Eduardo Federighi Baisi Chagas, Barbara de Oliveira Zanuso, Karina Quesada, Jesselina Francisco dos Santos Haber, Tereza Laís Menegucci Zutin, Luis Felipe Pimenta, Adriano Cressoni Araújo, Elen Landgraf Guiguer, Claudia Rucco P. Detregiachi, Marcia Gabaldi Rocha, Patrícia Cincotto dos Santos Bueno, Lucas Fornari Laurindo, Sandra M. Barbalho   +13 more
doaj   +1 more source

Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCR:LA-cp rat

Journal of Lipid Research, 2001
The corpulent JCR:LA-cp rat (cp/cp) is a useful model for study of the metabolic consequences of obesity and hyperinsulinemia. To assess the effect of hyperinsulinemia on VLDL secretion in this model, we measured rates of secretion of VLDL in perfused ...
Marshall B. Elam, Henry G. Wilcox, Lauren M. Cagen, Xiong Deng, Rajendra Raghow, Poonam Kumar, Murray Heimberg, James C. Russell   +7 more
doaj   +1 more source