Results 11 to 20 of about 159,989 (316)

Apolipoprotein D [PDF]

Gene, 2020
ApoD is a 25 to 30 kDa glycosylated protein, member of the lipocalin superfamily. As a transporter of several small hydrophobic molecules, its known biological functions are mostly associated to lipid metabolism and neuroprotection. ApoD is a multi-ligand, multi-function protein that is involved lipid trafficking, food intake, inflammation ...
Eric Rassart, Frederik Desmarais, Ouafa Najyb, Karl-F. Bergeron, Catherine Mounier   +4 more
openaire   +2 more sources

Apolipoproteins and cancer [PDF]

Cancer Medicine, 2019
AbstractThe role of apolipoproteins in cardiovascular disease has been well investigated, but their participation in cancer has only been explored in a few published studies which showed a close link with certain kinds of cancer. In this review, we focused on the function of different kinds of apolipoproteins in cancers, autophagy, oxidative stress ...
Liwen Ren, Jie Yi, Wan Li, Xiangjin Zheng, Jinyi Liu, Jinhua Wang, Guanhua Du   +6 more
openaire   +3 more sources

Apolipoprotein M [PDF]

Lipids in Health and Disease, 2004
AbstractApolipoprotein M (apoM) is a 26-kDa protein that is mainly associated with high-density lipoprotein (HDL) in human plasma, with a small proportion present in triglyceride-rich lipoproteins (TGRLP) and low-density lipoproteins (LDL). Human apoM gene is located in p21.31 on chromosome 6 (chromosome 17, in mouse).
Nilsson-Ehle Peter, Zhang Xiaoying, Luo Guanghua, Xu Ning   +3 more
openaire   +3 more sources

Effect of Early Enteral Feeding on Apolipoprotein AI Levels and High-Density Lipoprotein Heterogeneity in Preterm Infants [PDF]

, 2001
Background/Aim: We have previously shown that infants receiving total parenteral nutrition have low apolipoprotein Al levels which are associated with high-density lipoprotein (HDL) class distributions as in lecithin:cholesterol acyltransferase ...
Berthold Koletzkob, Koletzko, Berthold, Yvonne Göbelb, Genzel-Boroviczény, Orsolya, Göbel, Yvonne, Orsolya Genzel-boroviczénya   +5 more
core   +1 more source

The effect of apolipoprotein(a)-, apolipoprotein E-, and apolipoprotein A4- polymorphisms on quantitative lipoprotein(a) concentrations [PDF]

Twin Research, 2000
AbstractThe effects of apolipoprotein (a), apolipoprotein-E, and apolipoprotein-A4 isoforms on quantitative lipoprotein(a) [Lp(a)] levels were assessed in a sample of 142 Dutch families consisting of two parents and their adolescent twin offspring. A total heritability of 95% was estimated for plasma Lp(a) concentrations.
Boomsma, D. I., Knijff, P., Kaptein, A., Labeur, C., Martin, N. G., Havekes, L. M., Princen, H. M.   +6 more
openaire   +5 more sources

Apolipoprotein AIV gene variant S347 is associated with increased risk of coronary heart disease and lower plasma apolipoprotein AIV levels [PDF]

, 2003
The impact of common variants in the apolipoprotein gene cluster (APOC3-A4-A5) on prospective coronary heart disease (CHD) risk was examined in healthy UK men. Of the 2808 men followed over 9 years, 187 had a clinically defined CHD event.
Hawe, E., Miller, G.J., Hawe, Emma, Nicaud, V., Wong, W.-M.R., Wong, Wai-man R., Humphries, S.E., Li, Lai K., Li, L.K., Talmud, P.J., Nicaud, Viviane, Miller, George J., Pennacchio, Len A., Talmud, Philippa J., Pennacchio, L.A., Humphries, Steve E.   +15 more
core   +1 more source

Genetic variants in Apolipoprotein AV alter triglyceride concentrations in pregnancy. [PDF]

, 2003
BACKGROUND: Triglyceride concentrations are raised in pregnancy and are considered a key fetal fuel. Several gene variants are known to alter triglyceride concentrations, including those in the Apolipoprotein E (ApoE), Lipoprotein Lipase (LPL), and most ...
Andrew T Hattersley, Beatrice Knight, Kirsten J Ward, Ward Kirsten J, Knight Beatrice, Hattersley, Andrew T, Ward, Kirsten J, Maurice B Salzmann, Timothy M Frayling, Frayling, Timothy M, Beverley Shields, Shields, Beverley, Salzmann Maurice B, Hattersley Andrew T, Shields Beverley, Frayling Timothy M, Knight, Beatrice, Salzmann, Maurice B   +17 more
core   +1 more source

Liver X receptors are regulators of adipocyte gene expression but not differentiation

Journal of Lipid Research, 2004
The liver X receptors α and β (LXRα and LXRβ) have been shown to play important roles in lipid homeostasis in liver and macrophages, however, their function in adipose tissue is not well defined.
Sarah Hummasti, Bryan A. Laffitte, Michael A. Watson, Cristin Galardi, Lily C. Chao, Lakshman Ramamurthy, John T. Moore, Peter Tontonoz   +7 more
doaj   +1 more source

IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study. [PDF]

, 2015
IgG anti-apolipoprotein A-1 (IgG anti-apoA-1) antibodies are present in patients with systemic lupus erythematosus (SLE) and may link inflammatory disease activity and the increased risk of developing atherosclerosis and cardiovascular disease (CVD) in ...
Davari, M, Yiannis Ioannou, Isenberg, D, Paul Bassett, Rahman, A, David Isenberg, Anisur Rahman, Maria Davari, Alber, KF, Ioannou, Y, Oliver Leach, Giles, I, Bassett, P, Karim Alber, Ian Giles, Leach, O, Sara Croca, Chambers, S, Croca, S, Sharon Chambers   +19 more
core   +1 more source

Varied Relationship of Lipid and Lipoprotein Profiles to Liver Fat Content in Phenotypes of Metabolic Associated Fatty Liver Disease

Frontiers in Endocrinology, 2021
BackgroundProgressive overloads of intrahepatic triglycerides are related to metabolic dysregulation of multiple lipid and lipoprotein profiles, but whether similar dose effects are found in each subtype of metabolic associated fatty liver disease (MAFLD)
Tingfeng Wu, Junzhao Ye, Congxiang Shao, Fuxi Li, Yansong Lin, Qianqian Ma, Wei Wang, Shiting Feng, Bihui Zhong   +8 more
doaj   +1 more source