Results 1 to 10 of about 161,796 (303)
Molecules, 2021 Beta (β)-amyloid (Aβ) is a causative protein of Alzheimer’s disease (AD). In the pathogenesis of AD, the apolipoprotein (apo) A-I and high-density lipoprotein (HDL) metabolism is essential for the clearance of Aβ.
Kyung-Hyun Cho
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Medicines, 2021 The composition and properties of apolipoprotein (apo) A-I and apoA-II in high-density lipoproteins (HDL) might be critical to SARS-CoV-2 infection via SR-BI and antiviral activity against COVID-19.
Kyung-Hyun Cho
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Medical Sciences, 2021 Low serum high-density lipoproteins-cholesterol (HDL-C) levels and high blood pressure are linked to each other and are recognized as independent risk factors of cardiovascular disease and dementia. HDL can cross the blood–brain barrier to remove amyloid
Kyung-Hyun Cho, Jae-Ryong Kim
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Journal of Lipid Research, 1990 We have produced and characterized six murine monoclonal antibodies to human apolipoprotein A-I named A-I-9, A-I-12, A-I-15, A-I-16, A-I-19, and A-I-57. All monoclonal antibodies were specific for apolipoprotein A-I and bound between 55% and 100% of 125I-
S Marcovina +4 more
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Hepatic lipase:structure/function relationship, synthesis,and regulation
Journal of Lipid Research, 2002 Hepatic lipase (HL) is a lipolytic enzyme, synthesized by hepatocytes and found localized at the surface of liver sinusoid capillaries. In humans, the enzyme is mostly bound onto heparan-sulfate proteoglycans at the surface of hepatocytes and also of ...
Bertrand Perret +5 more
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Journal of Lipid Research, 1999 While low apolipoprotein A-I (apoA-I) levels are primarily associated with increased high density lipoprotein (HDL) fractional catabolic rate (FCR), the factors that regulate the clearance of HDL from the plasma are unclear.
Sylvie Braschi +3 more
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International Journal of Endocrinology, 2011 In this study, we investigate the effect of argan oil consumption on serum lipids, apolipoproteins (AI and B), CRP, and LDL susceptibility to oxidation in type 2 diabetic patients which are known to have a high level of cardiovascular risk due to lipid
M. M. Ould Mohamedou +5 more
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Apolipoprotein A-II regulates HDL stability and affects hepatic lipase association and activity
Journal of Lipid Research, 2004 The effect of apolipoprotein A-II (apoA-II) on the structure and stability of HDL has been investigated in reconstituted HDL particles. Purified human apoA-II was incorporated into sonicated, spherical LpA-I particles containing apoA-I, phospholipids ...
Jonathan Boucher +5 more
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Interaction of low-density lipoproteins of serum with hemin*†
Journal of Lipid Research, 1962 The interaction of low-density lipoproteins of human serum with hemin and the nature of the oxidative denaturation of low-density lipoproteins of serum catalyzed by hemin was studied by means of spectrophotometric and ultracentrifugal analyses and by ...
Toshiro Nishida, Fred A. Kummerow
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Evaluation of gel chromatography for plasma lipoprotein fractionation
Journal of Lipid Research, 1970 The fractionation of lipoproteins of normal and hyperlipidemic subjects on a column of 2% agarose was compared with ultracentrifugation and paper electrophoresis procedures. The following results were obtained.
Teizo Sata +3 more
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