Results 301 to 310 of about 22,660,301 (380)

Effect of oxidation on the properties of apolipoproteins A-I and A-II.

, 1988
G.M. Anantharamaiah, Thomas A. Hughes, M. Iqbal, Ali Gawish, Peter J. Neame, Mark F. Medley, Jere P. Segrest   +6 more
openalex   +1 more source

Genetic Determinants of the Familial Hypercholesterolaemia Phenotype

Annals of Human Genetics, EarlyView.
ABSTRACT Individuals with familial hypercholesterolaemia (FH) have severely elevated plasma concentrations of low‐density lipoprotein cholesterol (LDL‐C) from birth and as a consequence have an elevated morbidity and mortality due to the development of coronary heart disease (CHD).
Steve Eric Humphries, Marta Futema
wiley   +1 more source

Effects of a cardioprotective nutritional program on apolipoproteins and lipids in secondary cardiovascular disease prevention. [PDF]

Arch Endocrinol Metab
Marcadenti A, Bressan J, Moreira ASB, Machado RHV, Santos RHN, Amaral CK, Rogero MM, Capetini VC, Bersch-Ferreira AC.   +8 more
europepmc   +1 more source

Degradation of apolipoprotein II mRNA occurs via endonucleolytic cleavage at 5′-AAU-3′/5′-UAA-3′ elements in single-stranded loop domains of the 3′-noncoding region

, 1989
Roberta Binder, Sydney Hwang, R Ratnasabapathy, David L. Williams   +3 more
openalex   +1 more source

Clearance of Hepatitis C Viremia During Direct‐Acting Antiviral Therapy Leads to Rapid Changes in Lipid and Lipoprotein Metabolism

Alimentary Pharmacology &Therapeutics, EarlyView.
HCV clearance during direct‐acting antiviral therapy rapidly increases serum lipids and lipoproteins, potentially elevating cardiovascular risk. These metabolic changes, mediated by genes regulating hepatic lipogenesis, suggest that lipid levels should be closely monitored post‐SVR to assess long‐term cardiovascular implications.
Zahra Sarrafan‐Chaharsoughi, Varun Takyar, Sungyoung Auh, Gavin Nee, Ahmad Alawad, Brent S. Abel, Devika Kapuria, Colleen Byrnes, Anna Wolska, David E. Kleiner, Robert Shamburek, Alan T. Remaley, Marc G. Ghany   +12 more
wiley   +1 more source

Assessing the causal relationships between circulating metabolic biomarkers and breast cancer by using mendelian randomization. [PDF]

Front Genet
Wang B, Ling Y, Zhang H, Yang M.
europepmc   +1 more source

Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

Brain Pathology, EarlyView.
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie, Michael J. Miller, Celine Hardy, Ava R. Jarvis, Timothy F. Czajka, Lianna D'Brant, Natasha Rugenstein, Adam Waickman, Eain Murphy, David C. Butler   +9 more
wiley   +1 more source

Per- and polyfluoroalkyl substances, apolipoproteins and the risk of coronary heart disease in US men and women. [PDF]

Environ Health
Zhu L, Liu B, Hu Y, Wang M, Furtado JD, Rimm EB, Grandjean P, Sun Q.   +7 more
europepmc   +1 more source

Human amyotrophic lateral sclerosis/motor neuron disease: The disease‐associated microglial pathway is upregulated while APOE genotype governs risk and survival

Brain Pathology, EarlyView.
ALS/MND‐related inflammation is investigated in the motor cortex and spinal cord by both transcriptomics and immunohistochemistry. This reveals greater inflammation in the spinal cord and highlights the disease‐associated microglial (DAM) phenotype characterized by ApoE, TREM2, and TYROBP.
Bridget A. Ashford, Julie E. Simpson, Charlotte Dawson, Delphine Boche, Johnathan Cooper‐Knock, Paul R. Heath, Daniel Fillingham, Charlie Appleby‐Mallinder, Wenbin Wei, Mark Dunning, J. Robin Highley   +10 more
wiley   +1 more source

Porcine Sub-Retinal Pigment Epithelium Deposits: A Model for Dry Age-Related Macular Degeneration With Comparison to Human Drusen. [PDF]

Invest Ophthalmol Vis Sci
Shaw EM, Anderson DM, Periasamy R, Schey KL, Curcio CA, Lipinski DM.   +5 more
europepmc   +1 more source