The Effects of PPAR Agonists on Atherosclerosis and Nonalcoholic Fatty Liver Disease in ApoE−/−FXR−/− Mice [PDF]
Endocrinology and Metabolism, 2021 Background Farnesoid X receptor (FXR), a bile acid–activated nuclear receptor, is a potent regulator of glucose and lipid metabolism as well as of bile acid metabolism.
Yenna Lee +7 more
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Alzheimer's disease related heart structural and functional damage
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 Alzheimer's disease (AD) is a common neurological degenerative disease that can cause structural and functional abnormalities of the heart. Amyloid⁃β protein (Aβ) and AD⁃related gene variants play important roles in the pathophysiological changes of the ...
Shu⁃yu LIU, Wei ZHANG
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The Association between Apolipoprotein E Genotypes and Serum Malondialdehyde Level with End-Stage Renal Disease [PDF]
Iranian Journal of Medical Sciences, 2023 Background: The Apolipoprotein E (ApoE) polymorphism plays an important role in the pathophysiology of end-stage renal disease (ESRD). Additionally, ApoE may contribute to the progression of oxidative stress.
Daryoush Pourmand +3 more
doaj +1 more source
Arquivos de Neuro-Psiquiatria, 2022 Background Some studies show an association between the apolipoprotein E ε4 allele (ApoEε4) and obstructive sleep apnea syndrome (OSAS), and other studies, an association between ApoEε4 and excessive daytime sleepiness (EDS), but there are no data in the
Fernanda Maurer Balthazar +4 more
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Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses. [PDF]
PLoS ONE, 2015 Apolipoprotein E (ApoE), an exchangeable apolipoprotein, is necessary for production of infectious Hepatitis C virus (HCV) particles. However, ApoE is not the only liver-expressed apolipoprotein and the role of other apolipoproteins for production of ...
Kathrin Hueging +11 more
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Aqueous Humor Apolipoprotein Concentration and Severity of Diabetic Retinopathy in Type 2 Diabetes
Mediators of Inflammation, 2022 An imbalance of plasma apolipoproteins has been linked to diabetic retinopathy (DR); however, there is scarce information regarding their presence in the aqueous humor (AH) and their role in DR.
Lucia Saucedo +4 more
doaj +1 more source
Journal of Lipid Research, 1985 Like rat C apolipoproteins, each of the C apolipoproteins from human blood plasma (C-I, C-II, C-III-1, and C-III-2) bound to small chylomicrons from mesenteric lymph of estradiol-treated rats and inhibited their uptake by the isolated perfused rat liver.
E Windler, R J Havel
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The N-Terminus of Apolipoprotein A-V Adopts a Helix-Bundle Molecular Architecture [PDF]
, 2008 Previous studies of recombinant full-length human apolipoprotein A-V (apoA-V) provided evidence of the presence of two independently folded structural domains.
Beckstead, J. A. +6 more
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Peripheral blood mitochondrial DNA content in relation to circulating metabolites and inflammatory markers: a population study [PDF]
, 2017 Mitochondrial DNA (mtDNA) content might undergo significant changes caused by metabolic derangements, oxidative stress and inflammation that lead to development and progression of cardiovascular diseases.
Brguljan-Hitij, Jana +13 more
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Jornal Vascular Brasileiro, 2011 INTRODUCTION: The Saudi population is renowned for their unhealthy diet and physical inactivity. OBJECTIVE:To investigate apolipoproteins B (apo B), A-I (apo A-I) and B/A-I as risk factors that might be associated with increased incidence of the coronary
Mohmed Ashmaig +4 more
doaj +1 more source