Results 11 to 20 of about 37,409 (305)

Effect of APOE ε4 allele on levels of apolipoproteins E, J, and D, and redox signature in circulating extracellular vesicles from cognitively impaired with no dementia participants converted to Alzheimer's disease [PDF]

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021
Introduction The substantial link between apolipoprotein E (APOE) ε4 allele and oxidative stress may underlie enhanced Alzheimer's disease (AD) risk. Here, we studied the impact of APOE ε4 on the level of apolipoproteins with antioxidant activities along
Mohamed Raâfet Ben Khedher, Mohamed Haddad, Danielle Laurin, Charles Ramassamy   +3 more
doaj   +2 more sources

Exploring the evolving role of apolipoproteins in oncology: global trends and emerging frontiers [PDF]

Journal of Cancer Research and Clinical Oncology
Background Metabolic reprogramming, especially lipid metabolism, is crucial in cancer progression and treatment resistance. Apolipoproteins are crucial targets for research as they regulate autophagy, oxidative stress, and chemoresistance.
Dianzhe Tian, Zixuan Hu, Zuyi Yang, Lvyuxing Zhao, Haitao Zhao, Xinting Sang, Shunda Du, Yunping Luo, Lei Zhang, Yiyao Xu, Xin Lu   +10 more
doaj   +2 more sources

Changes in apolipoproteins following ingestion of a beverage delivering β-hydroxybutyrate: results from a randomized placebo-controlled trial [PDF]

Frontiers in Nutrition
BackgroundApolipoproteins play important roles in the metabolism of triglyceride-rich lipoproteins. Ketone monoester β-hydroxybutyrate (KEβHB) has been shown to reduce the circulating levels of remnant cholesterol and triglycerides.
Yutong Liu, Wandia Kimita, Sakina H. Bharmal, Maxim S. Petrov   +3 more
doaj   +2 more sources

Lipid-free Antigen B subunits from echinococcus granulosus: oligomerization, ligand binding, and membrane interaction properties [PDF]

, 2015
Background: The hydatid disease parasite Echinococcus granulosus has a restricted lipid metabolism, and needs to harvest essential lipids from the host.
Córsico, Betina, Ferreira, Ana M., Franchini, Gisela R., Kennedy, Malcolm W., Pórfido, Jorge L., Silva-Álvarez, Valeria   +5 more
core   +5 more sources

A common Hpa I RFLP of apolipoprotein C-I increases gene transcription and exhibits an ethnically distinct pattern of linkage disequilibrium with the alleles of apolipoprotein E

Journal of Lipid Research, 1999
Apolipoprotein (apo) C-I is a constituent of triglyceride-rich lipoproteins (TGRL) that interferes with their hepatic clearance. Functional polymorphism in the apoC-I gene has not been established.
Yan Xu, Lars Berglund, Rajasekhar Ramakrishnan, Richard Mayeux, Colleen Ngai, Steven Holleran, Benjamin Tycko, Todd Leff, Neil S. Shachter   +8 more
doaj   +1 more source

Postprandial apoE isoform and conformational changes associated with VLDL lipolysis products modulate monocyte inflammation. [PDF]

, 2012
ObjectivePostprandial hyperlipemia, characterized by increased circulating very low-density lipoproteins (VLDL) and circulating lipopolysaccharide (LPS), has been proposed as a mechanism of vascular injury.
Altman, Robin, Budamagunta, Madhu S., den Hartigh, Laura J., Hutchinson, Romobia, Lagerstedt, Jens,, Lund University., Lund University., Petrlova, Jitka,, Rutledge, John C., Tetali, Sarada D., Voss, John C.   +10 more
core   +3 more sources

Lipid and apolipoprotein concentrations in prenodal leg lymph of fasted humans: associations with plasma concentrations in normal subjects, lipoprotein lipase deficiency, and LCAT deficiency

Journal of Lipid Research, 2000
The extent to which lipid and apolipoprotein (apo) concentrations in tissue fluids are determined by those in plasma in normal humans is not known, as all studies to date have been performed on small numbers of subjects, often with dyslipidemia or ...
M.N. Nanjee, C.J. Cooke, W.L. Olszewski, N.E. Miller   +3 more
doaj   +1 more source

The Development of a Direct Homologous Radioimmunoassay for Serum Cortisol [PDF]

, 1981
Peer ...
Giesemann, G., Müller, O. A., Scriba, Peter Christian, Stalla, G., Wood, W. G.   +4 more
core   +2 more sources

Apolipoprotein E and Alzheimer's Disease [PDF]

Annual Review of Neuroscience, 1995
The apolipoprotein E locus (APOE) is associated with variations in the age of onset and risk of Alzheimer's disease. The APOE4 allele increases the probability of disease at an earlier age. In contrasL the APOE3 and APOE2 alleles decrease the probability of disease and increase the age of onset. Therefore the metabolism of apolipoprotein E is relevant
W J, Strittmatter, A D, Roses
openaire   +3 more sources

Hepatitis C virus relies on lipoproteins for its life cycle [PDF]

, 2016
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino, DI CAPRIO, Giorgia, Fimia, Gian Maria, Grassi, Germana, Ippolito, Giuseppe, Tripodi, Marco   +5 more
core   +1 more source