Results 51 to 60 of about 319,397 (302)

Synergistic p53 Pathway Activation Through Sono‐Gene Therapy Induced by Ultrasound‐Triggered Theranostic Mesoporous Nanoparticles

Advanced Science, EarlyView.
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Song Ning, Shuting Huang, Xiaoxuan Wang, Rui Liu, Yuye Fu, Suyun Li, Jie Li   +11 more
wiley   +1 more source

Las metamorfosis de Dafne y Apolo en cuatro fábulas áureas [PDF]

Acta Iassyensia Comparationis
En este artículo evidenciaremos las metamorfosis que experimen- tan Dafne y Apolo en cuatro fabulas mitológicas de los Siglos de Oro que tratan sobre el mito ovidiano.
CHANUT-CHAIZE KÉVIN
doaj   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

Apollo Belenos on Norican and Tauriscan coins

Arheološki Vestnik, 2016
The head on the obverse of Norican and Tauriscan coins is often casually identified as Apollo’s, mainly based on the god’s appearance on suggested prototypes for these coins.
Tomislav Bilić
doaj  

Dancing Through Mythological Threads: Unraveling the Symbolism of Chechen Dance

Sakarya İletişim, 2023
The incorporation of mythology into Chechen cultural practices and rituals, particularly in the realm of traditional dances, holds significant importance.
Maysa Bakeer
doaj  

Characterizing the resolution and throughput of the Apollo direct electron detector

Journal of Structural Biology: X, 2023
Advances in electron detection have been essential to the success of high-resolution cryo-EM structure determination. A new generation of direct electron detector called the Apollo, has been developed by Direct Electron.
Ruizhi Peng, Xiaofeng Fu, Joshua H. Mendez, Peter S. Randolph, Benjamin E. Bammes, Scott M. Stagg   +5 more
doaj   +1 more source

GMOD/Apollo: 2.6.5

, 2021
This release contains a fix that caused users to not be able to build due to a change to the Grails servers. See grails/grails-core#11825. If you are not able to upgrade Apollo to this version but still are experiencing build failures, you can update ...
S2KFan, Cory Maughmer, The Gitter Badger, Nathan Dunn, Liam Gretton, Kim Rutherford, Aymeric Naômé, luke, Gregg Helt, Eric Y, Helena, hsiao yi, Robert Syme, Rasmus Olofzon, Garrett Stevens, Monica Munoz-Torres, childers, Robert Buels, Justin Reese, Mikkel Christensen, Tim Stickland, rbelnap, NehaVC, Stephen Ficklin, Michael Paulini, Anthony Bretaudeau, Yating Liu, Jun-Wei Lin, Deepak, Colin Diesh   +29 more
core   +1 more source

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source

A New Lunar Crustal Thickness Model Constrained by Converted Seismic Waves Detected Beneath the Apollo Seismic Network

Geophysical Research Letters
Analysis of conversions between compressional and shear waves is a workhorse method for constraining crustal and lithospheric structure on Earth; yet, such converted waves have not been unequivocally identified in seismic data from the largest events on ...
D. Kim, V. Lekić, M. A. Wieczorek, N. C. Schmerr, G. S. Collins, M. P. Panning   +5 more
doaj   +1 more source