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Stimulants for disorders of consciousness in the intensive care unit: a randomized, placebo-controlled trial. [PDF]
Othman MH +29 more
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Glucuronidation of apomorphine
Apomorphine, a dopaminergic receptor agonist, is largely used in the therapy of Parkinson's disease. In this study, we characterized the glucuronidation of apomorphine and other catechols in rat liver and brain microsomes, using UDP-[U-14C]glucuronic acid and separation of the glucuronides formed by a thin layer chromatographic method.
R S, El-Bachá +4 more
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Pharmacology and Neurochemistry of Apomorphine
1978Publisher Summary This chapter discusses the pharmacology and neurochemistry of apomorphine. Apomorphine was first employed as a powerful emetic agent. Apomorphine can be obtained by the acid-catalyzed rearrangement of morphine and by total synthesis.
DI CHIARA, GAETANO, GESSA GL
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