Results 61 to 70 of about 590 (262)

La conversion à l’époque carolingienne

Cahiers d'Études du Religieux- Recherches Interdisciplinaires, 2011
In the Carolingian times, the conversion of peoples is mostly a collective phenomenon of adhesion to a political and cultural system, prompted by the political and military initiatives of Frank sovereigns and their missionaries, such as Anschary ...
Raffaele Savigni
doaj   +1 more source

War on paper: A critical discourse analysis of war reporting in Ethiopia. [PDF]

Heliyon, 2023
Nigatu BA.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Becoming Non-Religious: Exploring the Emotional Experiences of Apostasy and Refugee Status Determination

Secularism and Nonreligion
Leaving religion is a profoundly emotional process that is experienced and expressed in various ways. Those labelled as ‘apostates’ (individuals who leave a religion) in societies with restrictions on blasphemy and/or apostasy undergo a particularly ...
Lucy Elizabeth Potter
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

APOSTASY PUNISHMENT IN ISLAMIC SCHOLARLY DISCOURSE: PERSPECTIVES AND IMPLICATIONS IN THE MALAYSIAN CONTEXT

Malaysian Journal of Syariah and Law
This study explores the current academic debate on the punishment for apostasy within Islamic scholarship, focusing specifically on the Malaysian context.
Razali Musa, Kauthar Razali, Anis Sahira Mohamad Fakhrulrozi, Mohd Safri Ali, Muhammad Firdhaus Zulkifli, Nur Syahirah Mohammad Nasir   +5 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Faith and Freedom: The Qur’anic Notion of Freedom of Religion vs. the Act of Changing Religion and Thoughts on the Implications for Malaysia

Religions, 2016
The issue of freedom of religion has always been situated at the intersection between human rights, personal freedom of choice, religious belief and apostasy.
Siti Zubaidah Ismail, Muhamad Zahiri Awang Mat   +1 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source