Results 81 to 90 of about 590 (262)

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Can a case be made for “unlearning” in the study of religions?

open access: yesApproaching Religion
The concept of “unlearning” has been positively endorsed in both self-help literature and organizational research, but has yet to be discussed in the study of religions.
Kim Knott
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Zina ve İrtidad Suçları Bağlamında İslâm Ceza Hukukunda Cinsiyetin Cezâî Müeyyideye Etkisi

open access: yesBurdur İlahiyat Dergisi
İslâm hukukunda kamu ve kul haklarını ihlal edenlere öngörülen bazı cezaların bizzat mutlak adalet sahibi Allah (c.c.) tarafından belirlenmesi, cezanın tatbikinde “eşitlik” ilkesinin gözetilmesini zorunlu kılmaktadır.
İbrahim Demircan
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The Punishment for Apostasy in an Established Islamic Tradition

open access: yesThe Islamic Culture, 2018
The punishment for apostasy is an established Islamic Tradition THe writes,All Muslim j urists agree that the apostate is to be puni.shed. How ever, they differ regarding the punishment itself.
Hafiz Shabbir Ahmed Jamie   +1 more
doaj  

Sarmad di Kashan (XVII sec.), poeta persiano emigrato in India, dalla multipla personalità etnica, linguistica, religiosa

open access: yesDive-In
The article explores the intercultural and interreligious dimension of the Persian poet Sarmad of Kashan (c. 1590-1660), who was of Jewish-Armenian origin but born in Persia, later converted to Islam and finally emigrated to India.
Carlo Saccone
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

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