Results 201 to 210 of about 2,163 (253)

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

open access: yesThe FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti   +11 more
wiley   +1 more source

Integration of a vertical voluntary medical male circumcision program into routine health services in Zimbabwe: A solution for sustainable HIV prevention. [PDF]

open access: yesPLOS Glob Public Health
Chung AM   +12 more
europepmc   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

open access: yesThe FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs   +9 more
wiley   +1 more source

A mixed-method study of feasibility and acceptability of the Dapivirine vaginal ring among adolescent girls and young women (AGYW) in selected Zimbabwean districts. [PDF]

open access: yesPLOS Glob Public Health
Taruberekera N   +9 more
europepmc   +1 more source

Development and pilot evaluation of a Psychosocial Oncology and Palliative Care Training program for nurses in Cameroon. [PDF]

open access: yesPalliat Care Soc Pract
Bassah N   +12 more
europepmc   +1 more source
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The apostolic and sub-apostolic writings: the New Testament and the Apostolic Fathers

2004
The expression 'Apostolic Fathers' corresponds to an idea of seventeenth century origin. The primitive Christian literature takes a variety of forms, but by far the most frequent form is that of the letter. In the Roman-Hellenistic world letters were a common, if not frequent, means of communication among ordinary folk, for personal or business ...
Frances Young   +2 more
exaly   +2 more sources

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