Results 121 to 130 of about 1,198,310 (289)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Habitat-dependent effect of a rare predator on apparent survival of male Black-headed Bunting

open access: yesAvian Conservation and Ecology, 2016
Both habitat changes and predation can cause population declines in farmland birds. Habitat changes may allow novel or invasive alien predators to establish populations in new environments, which can have major ecological consequences for native prey ...
Jelena Kralj   +4 more
doaj   +1 more source

Kittens in the Oven: Race Relations, Traumatic Memory, and the Search for Identity in Julia Alvarez’s \u3cem\u3eHow the García Girls Lost Their Accents\u3c/em\u3e [PDF]

open access: yes, 2010
The search for an ever-elusive home is a thread that runs throughout much literature by authors who have immigrated to the United States. Dominican authors are particularly susceptible to this search for a home because “for many Dominicans, home is ...
Carter, Natalie
core   +1 more source

Complex spatial organization in a simple model of resource allocation

open access: yes, 2000
A dynamical model for the distribution of resources between competing agents is studied. While global competition leads to the accumulation of all the resources by a single agent, local competition allows for a wider resource distribution. Multiplicative
Zanette, Damian H.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Review of SEAFDEC/AQD fish nutrition and feed development research [PDF]

open access: yes, 1996
Research on fish nutrition and feed development at SEAFDEC Aquaculture Department has focused on three major areas: nutrient requirements and their interrelationships, digestive enzymes and digestibility, and practical feed development for important ...
Millamena, Oseni M.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Economic Policy and Desertification in Arid and Semi-arid Developing Countries [PDF]

open access: yes
Environmental degradation in arid and semi-arid regions often results from trade-offs between immediate and long-term needs. Ecological (and ultimately economic) benefits of restrained, sustainable resource use are well-understood by scientists, and are ...
Mark Speece
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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