Results 91 to 100 of about 16,073 (275)
The Faith, Hope and Charity Triad through Onomastic Nomination (with Reference to Eastern Slavonic Languages) [PDF]
Вопросы ономастики, 2011 The article analyzes the Вера, Надежда, Любовь (corresponding to the English Faith, Hope and Charity) proper names, and their Eastern Slavonic equivalents, viewed upon through the prism of correspondence to the appellative homonyms, designating the key ...
Olga V. Gerasimovich
doaj
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Cavernous haemangioma and mid trimester pregnancy loss leading to severe haemorrhage and hysterectomy: a case report and review of literature. [PDF]
Facts Views Vis Obgyn, 2023 Gallo A +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Appellative strategies in modern French printed advertising: intercultural analysis
Russian journal of linguistics: Vestnik RUDN, 2013 The article deals with the appellative strategies, reflecting French national peculiarities in modern French printed advertising.
A S Borisova, N S Naydenova
doaj
Acral findings during the COVID-19 outbreak: Chilblain-like lesions should be preferred to acroischemic lesions. [PDF]
J Am Acad Dermatol, 2020 Piccolo V, Bassi A.
europepmc +1 more source
Sexually Transmitted Infections and Health Literacy: A Community-Based Preventive Program. [PDF]
J Prim Care Community Health, 2023 Sul S +4 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source