Results 81 to 90 of about 1,462 (303)

PERSONALITY TYPE AND TRANSLATION PERFORMANCE OF PERSIAN TRANSLATOR TRAINEES

open access: yesIndonesian Journal of Applied Linguistics, 2017
The study investigated the relationship between the personality typology of a sample of Iranian translation students and their translation quality in terms of expressive, appellative, and informative text types.
Reza Shaki, Masood Khoshsaligheh
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Usage of Electronic Sources of Historical Czech for Formal Description of Appellative-Noun Declension

open access: yes, 2015
Characteristic of the tools and sources available in The Department of Language Development, which were used for the description of appellative-noun declension in the oldest period of the Czech language development (1300–1500): Old-Czech (or internal ...
Lehečka, Boris
core  

Gender and conversational discourse in the Hispanic context: the expression of male solidarity by means of the appellative particle macho among the Galician workers in a factory

open access: yes, 2011
En la línea de los estudios sobre género y discurso más recientes, que se interesan por el habla masculina prestando atención tanto a sus diferencias como a sus posibles similitudes con la interacción femenina, el presente artículo aborda el papel del ...
Acuña Ferreira, Virginia
core   +1 more source

Functioning of Vocatives in the Family Discourse (based on Oirat and English language)

open access: yesOriental Studies, 2018
The article deals with address terms that function in family discourse. The material was collected through means of interviewing. There is made a tentative attempt of comparative analysis of vocatives in English and still underreasearched Oirat languages.
Andrey Radionov
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

CLASSIFICATION OF THE APPELLATIVE LEXICON BASED ON FEMININE AND GIRLS’ NAMES ACCORDING TO LEXICAL-SEMANTIC GROUPS IN UZBEK LANGUAGE

open access: yes
This article discusses the appellative vocabulary (homonyms), which are considered the lexical basis of Uzbek female names, and their classification according to lexical-semantic groups.
Djuraeva Yulduz
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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