Results 61 to 70 of about 1,717 (247)
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Egy újabb tárgynévtípus: a 4-es metró fúrópajzsainak névadásáról
A recent type of object name: naming shields of the Budapest Underground’s 4th line This paper presents a recent type of object name: it discusses the international and Hungarian practices of giving names to shields used in construction work.
Judit Raátz
doaj +1 more source
Croatian Masculine Proper Names of Latin Origin and Their Equivalents of Croatian Origin
The research object of the present text is represented by Polish proper names, derived from a Roman mythological name. The authors’ aim is to present a full list of them and their initial meaning.
Gergana Petkova , Vanya Ivanova
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
The article is devoted to the study of surnames of the historical territory of the Rivne region in Ukraine with the suffixes -uk-, -yuk-, -chuk- in the context of Ukrainian-Polish studies.
Світлана [Svitlana] Шийка [Shyika]
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Ewald Müller Vornamen als appellative Personenbezeichnungen
Kirja-arvioMüller, Ewald: Vornamen als appellative ...
Penttilä, Aarni
core
Polish Proper Names Derived from a Latin Mythological Name
The research object of the present text is represented by Polish proper names, derived from a Roman mythological name. The authors’ aim is to present a full list of them and their initial meaning.
Gergana Petkova , Vanya Ivanova
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source

