Results 91 to 100 of about 1,462 (303)
Spaghetti Meat Abnormality in Broilers: Current Understanding and Future Research Directions. [PDF]
Front Physiol, 2021 Baldi G, Soglia F, Petracci M.
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2019 The research of a modern colloquial discourse is one of up to date’s steam. The articleshows specific nominative features of addressee in a modern Ukrainian discourse.
Бойко, І. О.
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A tulajdonnév köznevesülésének jelentésváltozási folyamatai
Névtani Értesítő, 2008 Semantic changes in the process of appellativisation of proper nouns This paper deals with the semantic processes that take place during the transition of a proper noun to an appellative (i.e. during appellativisation).
Stefanie Seifert
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
, 2022 Українські науковці всебічно досліджують комплекс засобів номінації, аналізуючи функційну значущість відповідних одиниць для тексту, їхню семантичну наповненість, особливості словотворення, вплив історичного й соціального складників та ін.
Состіна, О. М.
core
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
, 2014 Cases of a certain discrepancy between the known semantics of a derivational basis and the denotatum of a corresponding proper name are noted while analyzing the names of small geographical objects in the direction “from an appellative to an onym”.
Вадзім Шклярык +1 more
core +1 more source