ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Systematic review of phenotypes in McLeod syndrome and case report of a progressive supranuclear palsy in a female carrier. [PDF]
Braun AA, Jung HH.
europepmc +1 more source
Yield performance, mineral profile, and nitrate content in a selection of seventeen microgreen species. [PDF]
Di Gioia F +5 more
europepmc +1 more source
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao +6 more
wiley +1 more source
The impact of task complexity and translating self-efficacy belief on students' translation performance: Evidence from process and product data. [PDF]
Zhou X, Wang X, Liu X.
europepmc +1 more source
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec +6 more
wiley +1 more source
State-led agricultural subsidies drive monoculture cultivar cashew expansion in northern Western Ghats, India. [PDF]
Rege A, Lee JSH.
europepmc +1 more source
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
Intruding implements: a pictorial review of retained surgical foreign objects in neuroradiology. [PDF]
D'Amico A +4 more
europepmc +1 more source
The IL-17 family in diseases: from bench to bedside. [PDF]
Huangfu L, Li R, Huang Y, Wang S.
europepmc +1 more source

