Results 61 to 70 of about 743 (289)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Prūsistika K. O. Falko rankraštiniame palikime
Baltistica, 2011 PRUSSIAN PHILOLOGY IN K. O. FALK’S MANUSCRIPTS Summary On the basis of the preliminary analysis of Knut Olof Falk’s (1906-1990) manuscripts the conclusion can be drawn that the research into the Germanization of Prussian proper names ...
Bonifacas Stundžia
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
W poszukiwaniu tzw. centrum toponimii (wczesno)słowiańskiej – przypadek ziem polskich. Cz. I
LingVaria, 2017 In Search of the So-Called “Centre of Slavic Toponymy”. The Case of Poland. Part I This two-part paper presents the theoretical assumptions, and gives an account of the current progress of a Slavistic appendix which is being prepared by the present ...
Zbigniew Babik
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
HOMOGRAPHIC PROPER NAMES: ON PECULIARITIES OF PRONUNCIATION REGISTRATION
Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2020 The article considers phonetic variants of English proper names that comprise homographic groups, and some impairments during their registration in pronouncing dictionaries.
Natalya K. Ivanova, Rimma V. Kuzmina
doaj +1 more source
, 2018 The subject of the study is German traces in Melchior Wańkowicz’s reportages published in the “Anoda i katoda” [“The Anode and Cathode”] series, in the part titled “Kraj lat dziecinnych” [The Land of Childhood].
Guz, Marzena
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Ichthyological Hapax Legomena in Marcellus’ "De piscibus"
Studia Ceranea, 2019 Marcellus of Side, a physician and didactic poet of the second century AD, mentions fourteen exclusive ichthyonyms in the preserved fragment De piscibus, extracted from the 42-volume epic poem entitled Cheironides.
Konrad Tadajczyk, Katarzyna Gucio
doaj +1 more source