Results 51 to 60 of about 891 (242)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

On Appell-Vietoris Polynomials

open access: yes
In this paper we introduce a polynomial sequence (Vn(x))n≥0 involving the Vietoris’ number sequence and satisfying the Appell property. We derive several equivalent representations of Vn(x) and we deduce important relations closely related to the aforementioned Appell property.
Isabel Cação   +4 more
openaire   +3 more sources

Semantic features of appellatives denoting urban type of an inhabited place in West Germanic languages: contrastive aspect

open access: yes, 2022
Статтю присвячено семантичним особливостям апелятивів, які номінують міський тип населеного пункту у сучасних англійській та німецькій мовах. Лексика, яка вивчається у дослідженні, розглядається як лексико-семантична група на позначення населеного ...
Борисенко, Н. Д.   +1 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

On the Hydronym Kenozero [PDF]

open access: yesВопросы ономастики, 2011
The article puts forward a new etymological interpretation of the Kenozero toponym, functioning as a unifying name for a number of lakes in the Russian North, Karelia and Leningrad Region.
Kamill P. Volskiy
doaj  

Ancient place names of Greek and Latin origin in the Cilician plain [PDF]

open access: yesВестник Православного Свято-Тихоновского гуманитарного университета: Сериа III. Филология
The ancient toponymy of the Cilician Plain (Asia Minor) has a heterogeneous character, a significant part of the geographical names are of substrate origin, which reflects the rich ethnopolitical history of this region.
Alla Linko
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Niemieckie ślady w reportażach Melchiora Wańkowicza z tomu „Anoda i katoda”. Reportaże z części „Kraj lat dziecinnych” w perspektywie leksykalnej [PDF]

open access: yes, 2018
The subject of the study is German traces in Melchior Wańkowicz’s reportages published in the “Anoda i katoda” [“The Anode and Cathode”] series, in the part titled “Kraj lat dziecinnych” [The Land of Childhood].
Guz, Marzena
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Grammatical and Semantic Word-Formation of Toponymic Derivatives (on the Material of the Toponym “CИБИPЬ”)

open access: yesSHS Web of Conferences, 2018
The paper presents morphemic-derivational structure of toponymic derivatives (toponymy-derived formations) of proper name “Cибирь”. In revealed derived words authors identify morphemes, specify the methods of their production, provide statistics on word ...
Litovkina Anna M.
doaj   +1 more source

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