Results 141 to 150 of about 179,448 (308)
Discriminating complicated from uncomplicated appendicitis by ultrasound imaging, computed tomography or magnetic resonance imaging: systematic review and meta-analysis of diagnostic accuracy
BJS Open, 2020 Background Discriminating complicated from uncomplicated appendicitis is crucial. Patients with suspected complicated appendicitis are best treated by emergency surgery, whereas those with uncomplicated appendicitis may be treated with antibiotics alone. W. Bom, M. Bolmers, S. Gans, C. V. van Rossem, A. V. van Geloven, P. Bossuyt, J. Stoker, M. Boermeester +7 moresemanticscholar +1 more sourceWSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis
World Journal of Emergency Surgery, 2016 Acute appendicitis (AA) is among the most common cause of acute abdominal pain. Diagnosis of AA is challenging; a variable combination of clinical signs and symptoms has been used together with laboratory findings in several scoring systems proposed for ...S. di Saverio, A. Birindelli, M. D. Kelly, F. Catena, D. Weber, M. Sartelli, M. Sugrue, M. D. de Moya, C. Gomes, Aneel Bhangu, F. Agresta, Ernest E. Moore, K. Søreide, E. Griffiths, S. D. de Castro, J. Kashuk, Y. Kluger, A. Leppãniemi, L. Ansaloni, M. Andersson, F. Coccolini, R. Coimbra, K. Gurusamy, F. Campanile, W. Biffl, O. Chiara, F. Moore, A. Peitzman, G. Fraga, D. Costa, R. Maier, S. Rizoli, Z. Balogh, C. Bendinelli, R. Cirocchi, V. Tonini, A. Piccinini, G. Tugnoli, E. Jovine, R. Persiani, A. Biondi, T. Scalea, P. Stahel, R. Ivatury, G. Velmahos, R. Andersson +45 moresemanticscholar +1 more sourceFeasibility Evaluation of Commercially Available Video Conferencing Devices to Technically Direct Untrained Nonmedical Personnel to Perform a Rapid Trauma Ultrasound Examination. [PDF]
, 2019 Introduction: Point-of-care ultrasound (POCUS) is a rapidly expanding discipline that has proven to be a valuable modality in the hospital setting. Recent evidence has demonstrated the utility of commercially available video conferencing technologies ...Austin, Briahnna, Davis, Warren, Le, Danny Quy, Ma, Michael, Ramsingh, Davinder, Ricks, Cameron, Ringer, Mark +6 morecore +1 more sourceSebelipase Alfa Improves Aminotransferase Levels in Lysosomal Acid Lipase Deficiency: Data From an International Registry
Liver International, Volume 45, Issue 9, September 2025.ABSTRACT Background and Aims
In patients with lysosomal acid lipase deficiency (LAL‐D), elevations in alanine and aspartate aminotransferases (ALT, AST) are associated with liver damage. The objective of this analysis was to evaluate aminotransferase levels in patients treated with sebelipase alfa enzyme replacement therapy and untreated patients ...Lorenzo D'Antiga, Jennifer Evans, Emilio Ros, Florian Abel, Manisha Balwani, Don P. Wilson, William Balistreri +6 morewiley +1 more sourceEvaluation of appendicitis risk prediction models in adults with suspected appendicitis
British Journal of Surgery, 2019 Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK ...A. Bhangu, D. J. G. D. A. P. S. I. J. R. T. J. N. P. F. M. R. A. A. D. A. Nepogodiev Matthews Morley Naumann Ball Chauhan Bh, D. Nepogodiev, Jh Matthews, G. Morley, D. Naumann, A. Ball, P. Chauhan, S. Bhanderi, I. Mohamed, J. Glasbey, R. Wilkin, T. Drake, J. Clements, N. Blencowe, P. Herrod, F. Pata, M. Frasson, R. Blanco‐Colino, A. Soares, A. Bhangu, S. Jain, T. Amuthalingam, R. Tyler, E. Griffiths, T. Pinkney, O. Gee, D. Morton, A. Beggs, D. Beral, D. Bowley, N. Cruickshank, I. Daniels, E. Griffiths, S. Hornby, J. Lund, P. Marriott, P. Singh, N. Smart, D. Speake, C. Thompson, J. Torkington, A. Torrance, R. Vohra, O. Warren, D. Winter, G. Pellino, A. Sgró, A. Simioni, V. Farina, M. Podda, S. di Saverio, A. Birindelli, S. Pasquali, ItSURG, PT Surg, W. Bolton, C. Bradshaw, C. Chean, G. Harris, J. Haddow, N. Jamieson, S. McCain, J. Mason, D. Milgrom, G. Nana, MS Noor Mohamed, J. Brien, J. Pearce, M. Rabie, K. Sahnan, P. Sarmah, C. Skerritt, M. Ghazanfar, L. Sreedharan, S. Kabwama, R. Gray, I. Kamande, S. Nazarian, F. Dar, A. Misky, S. Arunachalam, CS Twum‐Barima, I. Mohamed, K. Connor, P. Coe, A. Kosti, M. Elshaer, D. Colvin, M. Charalambous, Ktd Yeung, L. Merker, T. Morrison, A. Thaventhiran, T. Gilbert, J. Clements, G. Hicks, S. Afshar, N. Mckinley, N. Assaf, T. Hanna, E. Macinnes, N. Thavanesan, A. Dubois, LK Palani‐Velu, S. Tezas, L. Yow, R. Radwan, M. Abdelrahman, Ka Lee, Z. Zarka, NA Mcdowall, Cy Tan, M. Venn, D. Ashmore, SE Whitehorn, A. Golder, A. Reddy, C. Delimpalta, OH Kay, Sm Shah, I. Eiben, C. Doyle, V. Tudyka, E. Issa, H. West, H. Brewer, E. Farrow, N. Taylor, C. Smart, N. Griffiths, C. Halkias, P. Vitish-Sharma, S. Knight, NG Mowbray, J. Olivier, K. Lee, K. Clement, D. Chrastek, N. Panda, M. Connor, S. Fahmy, ES Bryan, W. Ngu, S. Adegbola, Emmett J. Vaughan, W. Stupalkowska, L. Simmonds, A. Malik, A. Hussein, M. Karim, T. Singhal, R. Ormiston, V. Kung, M. Rabie, Jhee-Yoon Park, N. Lal, D. Worku, M. D'Auria, A. Ang, M. Orizu, E. Gammeri, E. Clough, C. Choy, S. Lawday, AJ Hann, D. Robinson, B. Wardle, D. Mcdonnell, D. Rutherford, LM Hickey, Agay Garg, S. Rezvani, CR Bell, F. Mahmood, S. Rehman, G. Donaldson, A. Peleki, L. Pearce, OL Sharp, S. Singh, D. Thompson, O. El‐Tayar, M. Hollyman, S. Rupasinghe, D. Toomey, M. Murray, N. Amtul, RJ Mersh, R. Newton, W. Al-Khyatt, G. Stephens, S. Abbas, M. Iqbal, CE Brown, S. Renshaw, K. Hureibi, UP Pullabatla‐Venkata, N. Donohoe, A. Myatt, R. Egan, K. Rangarajan, M. Trail, S. Mckay, Nft Engall, E. Jerome, D. Townsend, B. Patel, S. Pronin, N. Chandratreya, J. Choong, T. Mohamed, N. Hudson-Peacock, R. Manson, K. Hebbar, B. Mothe, C. Weegenaar, M. Saad, C. Bowman, F. Serventi, F. Fleres, C. Foppa, G. Pata, G. Baronio, D. Pertile, A. Lucchi, A. Sagnotta, I. Maretto, T. Campagnaro, M. Gatti, E. Gjoni, F. Roscio, M. Inama, F. Coccolini, F. Colombo, A. Avanzolini, S. Aresu, A. De‐Manzoni‐Garberini, D. Merlini, A. Chessa, N. Tamini, S. Mulas, N. Cillara, D. Coletta, J. Atzeni, E. Erdas, G. Gallo, E. Francone, P. Di Gioia, C. Bianchi, F. Ferrara, A. Biancafarina, S. Scabini, L. Marano, A. Miegge, D. Sasia, G. Savino, M. Scatizzi, F. d'Amico, G. Arcuri, L. Gavagna, G. Salamone, F. Tatulli, E. Goldin, M. Matos, A. Caldeira, J. Romano, J. Pereira, J. Azevedo, J. Azevedo, J. Simoes, Acq Silva, D. O’Leary, N. Kennedy, E. Quinn, A. Zhang, P. Neary, J. De-Marchi, BR O'Connor, K. Wijesundera, N. Foley, J. Wong, L. Tiedt, J. Bolger, T. Connelly, O. Ahmed, V. Vigorita, V. García, J. Arredondo, E. Redondo, B. Sainz, I. Aldrey, A. Landaluce-Olavarria, A. Gómez, E. Córdoba, MN Sánchez‐Fuentes, C. Cerdán-Santacruz, J. Beltrán-de-Heredia, M. Garcia, T. Vereš, A. García-Novoa, A. Abellán, L. García-Català, M. Ruiz-Marín, P. Menéndez, S. Roldán-Ortíz, JA Navas‐Cuéllar, D. Sabia, J. Gomez-Rosado, M. Navidad, C. Caula, E. Sánchez, E. Espín-Basany, D. Fernández‐Martínez, A. Bravo-Gutiérrez, C. Payá-Llorente, P. Dujovne, F. Lima, V. Soria-Aledo, C. Gómez, I. Pascual-Miguelañez, M. Muinelo, C. M. Álvarez, HJ Vargas‐Pierola, M. Vallvè-Bernal, J. Hidalgo-Rosas, JJ Arenal‐Vera, F. Sena-Ruiz, L. Sánchez-Guillén, P. Villarejo-Campos, L. Tallón-Aguilar, A. Garcea, J. Bennett, L. Whittaker, A. Gidwani, CK Byrnes, Smf Saunders, M. Shiwani, N. Ashraf, A. Venkatasubramaniam, K. Bevan, D. Mcarthur, A. Mustafa, J. Griffith, J. Blazeby, A. Charalabopoulos, W. Campbell, G. Reese, O. Warren, M. Peacock, D. Menzies, D. Jenner, N. Eardley, S. Yoong, M. Abulafi, H. Avalapati, R. Thompson, P. Nastro, R. Kochupapy, B. Stubbs, R. Mcintyre, J. Crozier, PK Patel, V. Pento, W. Beasley, C. Roxburgh, H. Youssef, R. Alexander, S. Denley, F. Di Franco, A. Quddus, A. Saha, I. Hunter, J. Hannay, V. Velchuru, G. Bond-Smith, Y. Salama, A. Bhargava, S. Panagiotopoulos, N. Watson, G. Garcea, A. Boddy, PG Dunning, G. Lloyd, S. Gurjar, J. Hill, B. Andrews, A. Singh, F. Ruzvidzo, G. Shingler, D. Mahon, S. Elgaddal, C. Payne, I. Shaikh, S. Dalmia, M. Nair, J. Finch, K. Chapple, S. Bawa, J. Watfah, C. Carden, R. Makhija, M. Rao, J. Sarveswaran, V. Vijay, S. Rekhraj, B. Knight, M. Siddiqui, J. Sebastian, P. Glen, S. Vakis, H. Ebied, R. Rajaram, J. Gray, D. Mcgrath, G. Faulkner, S. Gopalswamy, M. Varcada, A. Woodward, G. Williams, K. Szentpáli, R. Ravindran, C. Bronder, M. Thaha, A. Rate, V. Shetty, V. Rao, M. Sajid, B. Clements, R. Patel, C. Mason, G. Branagan, K. Maude, G. Kaur, A. Lyons, P. Ainsworth, R. Hagger, AZ Zadi, S. Maslekar, J. Kinross, S. Irukulla, W. Hawkins, S. Wheatstone, T. Magro, S. Bailey, G. Marshall, J. McCullough, G. Marangoni, E. Leung, C. Borg, S. Gopinath, J. Kirkby-bott, S. Yalamarthi, S. Mirza, M. Brett, S. Ramcharan, V. Pandey, B. Thava, S. Andreani, S. Sahay, B. Aravind, M. Downey, D. Nicol, P. Whitehouse, A. Sharma, N. Francis, P. Chitsabesan, D. Stewart, G. Norcia, E. Cucinotta, F. Cianchi, U. F. Romario, L. Taglietti, P. Capelli, G. Garulli, A. Parisi, D. Nitti, A. Guglielmi, A. Alonzo, IS Scandroglio, G. Moretto, L. Ansaloni, A. Pietrabissa, D. Foschi, N. Vettoretto, G. Ercolani, M. Coppola, E. Colangelo, E. Morandi, P. Niolu, M. Pala, M. Coletti, A. Pisanu, A. Nicolosi, G. Sammarco, S. Berti, P. Soliani, V. Tonini, M. Stella, G. Ceccarelli +499 moresemanticscholar +1 more sourceEfficacy, Safety, Pharmacokinetics, and Immunogenicity of ABBV‐154 in Adults With Glucocorticoid‐Dependent Polymyalgia Rheumatica: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial
Arthritis &Rheumatology, Volume 77, Issue 8, Page 1041-1051, August 2025.Objective
An unmet need exists for glucocorticoid‐sparing treatments for patients with polymyalgia rheumatica (PMR). The antibody‐drug conjugate ABBV‐154 comprises adalimumab conjugated to a glucocorticoid receptor modulator. We evaluated ABBV‐154 versus placebo in patients with glucocorticoid‐dependent PMR.Robert F. Spiera, Valerie Devauchelle‐Pensec, Claire E. Owen, Federico Díaz‐González, Tsutomu Takeuchi, Edit Drescher, Jaclyn Anderson, Dilek Arikan, Ronilda D'Cunha, Julie Parmentier, Denise T. Kruzikas, Weihan Zhao, Yang Yang, Karen Stellpflug, Frank Buttgereit +14 morewiley +1 more source