Results 81 to 90 of about 55,178 (309)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
An Application with webMathematica [PDF]
, 2003 There have been many technological dawns in the last 30 years, during which the desktop computer and the Internet have been developed. The importance of Internet in education, particularly using its Web is a well-recognized fact. A wealth of resources and techniques now exist which serve as a source both for exciting examples of new teaching practices,
openaire +2 more sources
Declaration of Intention of Louis D'Alessandro
, 1924 Declaration of Intention to become a citizen of the United States, as filled out and signed by: Louis D'Alessandro Applicant age: 26 Occupation: Tailor Country of Origin: Italy Date of Birth: 1st March 1897 Sailed to the US aboard the vessel: Pesaro
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Condition of and Structural Changes in the Energy Sector of Ukraine [PDF]
Problemi Ekonomiki, 2017 The article is dedicated to the analysis of the condition of Ukraine’s energy sector and its structural changes in the period 2000-2016. The dynamics of electric power production in Ukraine and the world, as well as the capacity utilization factor are ...
Miliutin Hlib V.
doaj
Frontiers in Psychology, 2017 Prior research suggests that interviewers play an important role in representing their organization and in making the interview a pleasant experience for applicants.
Annika Wilhelmy +3 more
doaj +1 more source
Applicant and Examiner Citations in US Patents: An Overview and Analysis [PDF]
Researchers studying innovation increasingly use indicators based on patent citations. However, it is well known that not all citations originate from applicants--patent examiners contribute to citations listed in issued patents--and that this could ...
Michelle Gittelman +2 more
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source