Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Effectiveness of the Enjoy-Breastfeeding Mom App on Breastfeeding Knowledge, Attitudes, Self-Efficacy, and Infant Responsiveness Among Thai Adolescent Mothers: A Three-Arm Randomised Controlled Trial. [PDF]
Nuampa S +4 more
europepmc +1 more source
Applicability and Application of Microscopic Traffic Simulations [PDF]
Die Dynamik des Verkehrsflusses zeigt unterschiedliche, komplexe räumliche und zeitliche Muster. Ein bekanntes Phänomen ist beispielsweise der abrupte und plötzliche Abfall der Durchschnittsgeschwindigkeit auf einem Streckenabschnitt, der zu Stauungen führt.
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Expression of concern: Engineering Pseudomonas protegens Pf-5 for nitrogen fixation and its application to improve plant growth under nitrogen-deficient conditions. [PDF]
PLOS One Editors.
europepmc +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Under pressure - a sensor-based analysis of simulated prehospital pressure dressing application for hemorrhage management. [PDF]
Brauckmann V +4 more
europepmc +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Assessment of pain and post-injection induration in children: A comparative study of cold application, manual pressure, and shot blocker techniques. [PDF]
Sasireka V, Bhuvaneswari G, Babu S.
europepmc +1 more source

