Results 131 to 140 of about 30,090,884 (357)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Controlling price volatility through financial innovation [PDF]

open access: yes
In this paper, the authors study the possibility of controlling asset price volatility through financial innovation in a three-period finite competitive exchange economy with incomplete financial markets and retrading.incomplete markets; financial ...
Alessandro, CITANNA, SCHMEDDERS, Karl
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Internet media planning : an optimization model [PDF]

open access: yes
Of the various media vehicles available for advertising, the internet is the latest and the most rapidly growing, emerging as the ideal medium to promote products and services in the global market.
KERBACHE, Laoucine, LEE, Janghyuk
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

A resource need and availability view of the make or ally choice: evidence from the worldwide aircraft industry 1945-2000 [PDF]

open access: yes
This paper investigates why firms choose to undertake product expansion through alliances with competitors rather than on their own.alliance; governance; resource; competence; expansion ...
Castaner, Xavier   +2 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Progress in fiber‐shaped zinc batteries: From structure, manufacturing, optimization to application

open access: yesInfoMat
Fiber‐shaped batteries, distinguished by their unique one‐dimensional architecture, offer ultra‐high flexibility, remarkable stretchability, and excellent knittability, rendering them highly appealing as energy storage solutions for smart wearable ...
Chongyang Luo   +9 more
doaj   +1 more source

Roles, authority and involvement of the management accounting function: a multiple case-study perspective [PDF]

open access: yes
Recent techniques and shifts in the environment are often foreseen as leading management accountants to adopt a business orientation. However, empirical evidence pointing to fundamental shifts in the roles played by management accountants remains ...
Lambert, Caroline, Sponem, Samuel
core  

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