Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Controlling price volatility through financial innovation [PDF]
In this paper, the authors study the possibility of controlling asset price volatility through financial innovation in a three-period finite competitive exchange economy with incomplete financial markets and retrading.incomplete markets; financial ...
Alessandro, CITANNA, SCHMEDDERS, Karl
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TreeView: an application to display phylogenetic trees on personal computers
R. Page
semanticscholar +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Internet media planning : an optimization model [PDF]
Of the various media vehicles available for advertising, the internet is the latest and the most rapidly growing, emerging as the ideal medium to promote products and services in the global market.
KERBACHE, Laoucine, LEE, Janghyuk
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
A resource need and availability view of the make or ally choice: evidence from the worldwide aircraft industry 1945-2000 [PDF]
This paper investigates why firms choose to undertake product expansion through alliances with competitors rather than on their own.alliance; governance; resource; competence; expansion ...
Castaner, Xavier +2 more
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Progress in fiber‐shaped zinc batteries: From structure, manufacturing, optimization to application
Fiber‐shaped batteries, distinguished by their unique one‐dimensional architecture, offer ultra‐high flexibility, remarkable stretchability, and excellent knittability, rendering them highly appealing as energy storage solutions for smart wearable ...
Chongyang Luo +9 more
doaj +1 more source
Roles, authority and involvement of the management accounting function: a multiple case-study perspective [PDF]
Recent techniques and shifts in the environment are often foreseen as leading management accountants to adopt a business orientation. However, empirical evidence pointing to fundamental shifts in the roles played by management accountants remains ...
Lambert, Caroline, Sponem, Samuel
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