Results 241 to 250 of about 19,951,400 (295)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Erratum: Recent advances in ternary Z-scheme photocatalysis on graphitic carbon nitride based photocatalysts

Frontiers in Chemistry
Frontiers Production Office
doaj   +1 more source

Strigolactone GR24 modulates citrus root architecture and rhizosphere microbiome under nitrogen and phosphorus deficiency. [PDF]

BMC Plant Biol
Soliman S, Rezk A, Rocha FI, Rodriguez-Ramos JC, Manoharan B, Wang Y, Han Z, Hale L, El-Kereamy A.   +8 more
europepmc   +1 more source

Core Levels, Band Alignments, and Valence-Band States in CuSbS₂ for Solar Cell Applications

, 2017
Thomas J. Whittles, T. D. Veal, Christopher N. Savory, Adam W. Welch, Francisco Willian de Souza Lucas, James T. Gibbon, Max Birkett, Richard J. Potter, David O. Scanlon, Andriy Zakutayev, V.R. Dhanak   +10 more
openalex   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

A Systematic Review of Smartphone Applications That Address Patient Care in the Peri-Operative Period. [PDF]

Healthcare (Basel)
El-Hadi H, Chan BL, Siu BW, Ko IC, Leung DK, Teoh JY, Chiu PK, Ng CF, Liu AQ.   +8 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Film mulching combined with chemical fertilizer increased rice yield by promoting the accumulation of photosynthetic substances in the vegetative growth stage. [PDF]

Sci Rep
Bai J, Fu X, Huang R, Dang K, Shao X, Zhang Q, Liang X, Geng Y, Guo L.   +8 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Clinical Outcomes and Safety Profile of a Novel Hyaluronic Acid/Alginate Hydrogel in Hand and Microsurgical Procedures. [PDF]

Plast Reconstr Surg Glob Open
Arquette C, Silverstein M, Ng MK, Safa B, Lin WC.   +4 more
europepmc   +1 more source