Results 61 to 70 of about 3,729,789 (244)

New Features for Child Metrics: Further Growth References and Blood Pressure Calculations

JCRPE, 2020
Many new features have recently been incorporated to ÇEDD Çözüm/Child Metrics, an online and freely accessible scientific toolset. Various auxological assessments can now be made with data of children with genetic diseases (Prader Willi syndrome, Noonan ...
Korcan Demir, Ergun Konakçı, Güven Özkaya, Belde Kasap Demir, Samim Özen, Murat Aydın, Feyza Darendeliler   +6 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Efficacy and feasibility of a digital speech therapy for post-stroke dysarthria: protocol for a randomized controlled trial

Frontiers in Neurology
BackgroundDysarthria is a motor speech disorder caused by various neurological diseases, particularly stroke. Individuals with post-stroke dysarthria experience impaired speech intelligibility, communication difficulties, and a reduced quality of life ...
Yuyoung Kim, Minjung Kim, Jinwoo Kim, Jinwoo Kim, Tae-Jin Song   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Room Temperature Wearable Gas Sensors for Fabrication and Applications

Advanced Sensor Research
The recent surge in demand for human–machine interaction (HMI), Internet of Things (IoTs), and artificial intelligence (AI) has created both opportunities and challenges for room‐temperature wearable gas sensors.
Yanan Xiao, He Li, Chen Wang, Si Pan, Junming He, Ao Liu, Jing Wang, Peng Sun, Fangmeng Liu, Geyu Lu   +9 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Massoia Lactone: Production Technologies, Multisectoral Applications, and Toxicological Evaluation [PDF]

BIO Web of Conferences
Massoia lactone is a delta-lactone that occurs naturally in the bark oil of Cryptocarya massoy, recognized for its sweet, coconut-like scent and extensive industrial applications.
Kartika I Gusti Agung Ayu, Ucche Sisca, Nugroho Agung Endro   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Foodomics Applications

, 2018
Foodomics is the discipline that studies the food and nutrition domains through the application and integration of advanced omics technologies. This chapter summarizes the different strategies used in Foodomics for data analysis as well as the existing limitations and challenges that still need to be overcome in this new discipline.
León, Carlos, Cifuentes, Alejandro, Valdés, Alberto   +2 more
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source