Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The Attributes and Practical Principle of Medical Professionalism
It is the most important thing at present for physicians to posses the qualification of medical professionalism. A lot of medical schools have made all-out efforts to develop leaders of medicine, who will be able to meet the needs of medical ...
연세대학교 의과대학
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Biomimetic scaffold and 3D bioprinting in dental application: A review. [PDF]
Subbiah U +5 more
europepmc +1 more source
Promoting Prognostic Model Application: A Review Based on Gliomas. [PDF]
Liang X +5 more
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Keratin from Animal By-Products: Structure, Characterization, Extraction and Application-A Review. [PDF]
Banasaz S, Ferraro V.
europepmc +1 more source
Modelling of Stem Cells Microenvironment Using Carbon-Based Scaffold for Tissue Engineering Application-A Review. [PDF]
Vitus V +2 more
europepmc +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Reverse engineering in medical application: literature review, proof of concept and future perspectives. [PDF]
Wakjira Y, Kurukkal NS, Lemu HG.
europepmc +1 more source
Prospect of DFT Utilization in Polymer-Graphene Composites for Electromagnetic Interference Shielding Application: A Review. [PDF]
Orasugh JT, Ray SS.
europepmc +1 more source

