Results 81 to 90 of about 2,303,351 (296)

Federal judicial review in Australia [PDF]

open access: yes, 2012
The report provides a detailed examination of Australia\u27s judicial review system, which is an important avenue of appeal for those affected by government decision making, and makes a number of recommendations aimed at improving its accessibility and

core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

[Application for Review of Discharge, Photograph #2]

open access: yes, 1963
Evidence photograph of a document found in Oswald's home. The document is titled "Application for Review of Discharge or Separation from the Armed Forces of the United States.
Dallas (Tex.). Police Department.
core  

Application-aware Intrusion Detection: A Systematic Literature Review and Implications for Automotive Systems - Supplementary Information

open access: yes, 2019
This data constitutes supplementary information for our publication "Application-aware Intrusion Detection: A Systematic Literature Review and Implications for Automotive Systems".
David Schubert (6887906)   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Resource Sector Perspectves on Canadian Competition Policy

open access: yes, 1979
This paper provides general background review and current update as to the legislative development of the existing Combines Investigation Act, concentrating on the application or non-application of the existing legislation to selected activities common ...
Prueter, William R.
core   +1 more source

Strategic group theory: review, examination and application in the UK pharmaceutical industry [PDF]

open access: yes, 2006
Purpose – The purpose of this paper is to consider the current status of strategic group theory in the light of developments over the last three decades.
Leask, Graham, Parker, David
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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