Results 121 to 130 of about 5,896,401 (303)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Mobile Support in CSCW Applications and Groupware Development Frameworks
International Journal of Interactive Mobile Technologies (iJIM), 2013 Computer Supported Cooperative Work (CSCW) is an established subset of the field of Human Computer Interaction that deals with the how people use computing technology to enhance group interaction and collaboration. Mobile CSCW has emerged as a result of the progression from personal desktop computing to the mobile device platforms that are ubiquitous ...
openaire +5 more sources
Embedding race equality and internationalising the curriculum:Abertay University case study [PDF]
, 2018 As part of the HEA Scotland embedding equality and diversity in the curriculum (EEDC) strategic enhancement project, Abertay University focused on developing an infrastructure for the embedding of race equality and the internationalising of their ...
Cameron, Andrea
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Research and Development Suggestion for Automatic Push-support Pipe Handling System
Shiyou jixie, 2018 The main features, main technical parameters of the push-support automatic pipe handling system and the field application of the main equipment are introduced.
Wang Dingya +5 more
doaj
Developing A Mobile Application to Determine the Psychological Wellness of University Students
Düzce Tıp Fakültesi Dergisiof university students.Material and Methods: Using an innovative and interdisciplinary approach, this study follows a rigorous methodology from September 2022 to June 2023.
Dilek Demirezen, Aysel Karaca
doaj +1 more source
Simulation models for autonomous rendezvous and capture [PDF]
Autonomous rendezvous and capture (AR&C) is a critical space technology with significant application to a variety of missions. Martin Marietta Astronautics Group (MMAG) has been developing AR&C technical capability in support of several recent NASA ...
Early, Sid M. +2 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
INTRODUCTION TO ZEND FRAMEWORK [PDF]
A software framework provides the skeleton of an application that can be customized by an application developer. Like software libraries, software frameworks aid the software developer by containing source code that solves problems for a given domain and
Dragos-Paul POP
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source