Results 131 to 140 of about 5,896,401 (303)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Programming patterns and development guidelines for Semantic Sensor Grids (SemSorGrid4Env)

, 2011
The web of Linked Data holds great potential for the creation of semantic applications that can combine self-describing structured data from many sources including sensor networks.
De Roure, David, Frazer, Alex J., Martinez, Kirk, Nagel, Bart, Page, Kevin R.   +4 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Development and Application of a Unplanned Extubation Assessment and Clinical Decision Support Information System

Risk Management and Healthcare Policy
Huayu Chen,1 Xiaowen Yang,2 Jifang Peng,3 Xianrong Xu,4 Yaping Li,1 Zirong Tong,5 Chunhong Gao5 1Department of Neurosurgery, First Affiliated Hospital with Nanjing Medical University Junior Nurse, Nanjing, Jiangsu, 210029, People’s Republic of China ...
Chen H, Yang X, Peng J, Xu X, Li Y, Tong Z, Gao C   +6 more
doaj  

Development of a Flask-based Application for Bank Customer Churn Prediction as a Decision Support Tool

Sistemasi: Jurnal Sistem Informasi
Customer churn prediction is a crucial aspect of the banking industry for maintaining customer loyalty and reducing the cost of acquiring new customers.
Suluh Arif Wibowo, Muhammad Rezky, Ali Ibrahim, Mira Afrina, Fathoni Fathoni   +4 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Development of chia gum/alginate-polymer support for horseradish peroxidase immobilization and its application in phenolic removal

Scientific Reports
Chia gum’s molecular structure with distinctive properties as well as the alginate-based hydrogel’s three-dimensionally cross-linked structure can provide a potent matrix for immobilization of enzyme.
Saleh A. Mohamed, Alshaimaa M. Elsayed, Hala A. Salah, Amal Z. Barakat, Roqaya I. Bassuiny, Heidi M. Abdel-Mageed, Azza M. Abdel-Aty   +6 more
doaj   +1 more source

Development of Postpartum Mobile Support Application (BebekveBiz)

Turkiye Klinikleri Journal of Nursing Sciences, 2021
Vesile KOÇAK, Emel EGE
openaire   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source