Results 81 to 90 of about 201,713 (268)

Application of the model reference adaptive control theory to an electrohydraulic servosystem.

Hydraulics & Pneumatics, 1987
The present study deals with the adaptive control of an electrohydraulic servomotor system. A model reference adaptive controller has been designed to compensate for parameter changes such as load and oil viscosity. A digital system has been adopted because the controller has to carry out a lot of multiplyinga nd integrating operations, and a discrete ...
INOUE, Masashi, TAKAHASHI, Koji, IKEO, Shigeru   +2 more
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Summary of the theory and modeling contributions at the 29th IAEA Fusion Energy Conference (FEC 2023)

Nuclear Fusion
The contributions in magnetic confinement fusion theory presented at the 29th Fusion Energy Conference (FEC 2023) are summarized here. This summary aims at providing an overview of the advances in the field and new directions in integrated modeling ...
Francesca M. Poli
doaj   +1 more source

H8 Model Predictive Control: theory and application

, 2005
"Future industrial systems will require control systems to be more reliable, autonomous, robust, and yet efficient. The emphasis of this thesis is to introduce a robust control algo­rithm definition that addresses the needs of future industrial environments. The proposed controller is based on an adaptive concept with a two-step approach.
openaire   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

MODELLING AND STUDY OF EVENT-DRIVEN FLOW MOVEMENTS IN THE MANUFACTURING OF WIRE HARNESSES USING ULTRASONIC WELDING FOR WIRES CONNECTION

Сучасні інформаційні системи, 2018
The development of the common control theory, organization and management of production systems and processes, computer information systems and technology, instrumental environments and development systems require development of new models, structures ...
Martin Stoychev Dimitrov
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Some applications of a result in control theory to economic planning models [PDF]

Weltwirtschaftliches Archiv, 1975
Einige Anwendungen eines Ergebnisses der Kontrolltheorie auf wirtschaftliche Planungsmodelle. — Neuere Ergebnisse hinsichtlich der notwendigen Bedingungen bei Problemen optimaler Kontrolle mit Nebenbedingungen in Form von Ungleichungen bei den Zustandsvariablen haben gezeigt, daβ fur eine besondere Klasse von Problemen der optimale Pfad innerhalb von ...
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source