Results 51 to 60 of about 569,602 (292)
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Pervasive Auto-Scaling Method for Improving the Quality of Resource Allocation in Cloud Platforms
Cloud resource provider deployment at random locations increases operational costs regardless of the application demand intervals. To provide adaptable load balancing under varying application traffic intervals, the auto-scaling concept has been ...
Vimal Raja Rajasekar, G. Santhi
doaj +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Business Process Outsourcing [PDF]
Business Process Outsourcing (BPO) is gaining widespread acceptance throughout the US, Europe, South America and Asia Pacific as the top executives of leading multinationals turn to outsourcing as a strategic management tool for improving corporate ...
Doina FOTACHE, Luminita HURBEAN
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
THE UTILIZATION OF INFORMATION AND COMMUNICATION TECHNOLOGY TO SUPPORT LEARNING-BASED PROCESS OF PDCA QUALITY ISO 9001: 2008 IWA2 [PDF]
Education Institution is the service provider institution, therefore the customers who get involved demanding the guarantee fulfill their needs suit to the promise have given by the company consistently and continuously.
Barnad, Barnad
core
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Patient-centered care and healthcare consumerism are the two most dominant ideas about the relationship between patients and providers in the United States.
Sung-Yeon Park PhD +4 more
doaj +1 more source
Cloud Based Application Development for Accessing Restaurant Information on Mobile Device using LBS
Over the past couple of years, the extent of the services provided on the mobile devices has increased rapidly. A special class of service among them is the Location Based Service(LBS) which depends on the geographical position of the user to provide ...
Shetty, Keerthi S., Singh, Sanjay
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source

