Results 91 to 100 of about 12,911,308 (318)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Department of Applied Mathematics and Statistics Newsletter, February 2, 2026
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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Applied psychology Part 4 Like a virgin
Original sin is only a poor stimulator of behaviour change. It's easy to understand that it seems rather unfair to blame a new-born for the major problems that humanity faces after several centuries of technological progress.
Graaf, de, JW (Jan Willem)
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Vienna Workshop’s Role in Linking Plastic art Aspects with Applied Ones
This article shows the most important tasks of the Vienna Workshop, in linking the plastic and applicable aspects together to unify arts in all fields. These arts had different objects and styles of artists and architectural designers, whose ideas and ...
Abir Arafeh
doaj
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Department of Applied Mathematics and Statistics Newsletter, January 26, 2026 [PDF]
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Department of Applied Mathematics and Statistics Newsletter, November 24, 2025
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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