Results 51 to 60 of about 12,095 (198)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Effects of Applied Behavior Analysis method on the performance of 5 to 10 year old autistic children in Farshchian Therapy Center of Hamadan in 1389 [PDF]
Ravānshināsī-i Afrād-i Istis̠nāyī, 2011 Objective: The objective of this study was to assess the effects of ABA treatment on the performance of Hamadan autistic children. Method: An applied research with an experimental design has been used.
doaj
Frontiers in Integrative Neuroscience, 2020 Background: The purpose of this study was to explore the question of the minimal amount of instructional time needed to still be effective by assessing the efficacy at mid-intervention of an early fundamental movement skill (FMS) intervention for ...
Isabella Theresa Felzer-Kim +1 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Primenjena PsihologijaThis study aimed to evaluate the academic skills (reading, mathematics, and writing) of students with autism spectrum disorder (ASD) who are benefiting from interventions based on applied behavior analysis (ABA-based) and students with ASD who are not ...
Brahim Nadir, Abdellatif El Farahi
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Behavioral SciencesBackground: Parental and caregiver stress represents a critical factor influencing family functioning and the quality of care in families of autistic children.
Marco Esposito +4 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Behavioral SciencesParental involvement in applied behavior analysis (ABA) interventions for children with autism spectrum disorder (ASD) is essential for treatment success, yet caregiver engagement remains inconsistent across clinical contexts.
Andres F. Mambuca
doaj +1 more source