Results 51 to 60 of about 2,839,840 (302)

Savoirs experts et idiome quotidien. Biens et vertus de la conception participative des velos de quartiers à Trois-Rivières [PDF]

open access: yesLes Ateliers de l’Ethique, 2010
This paper analyzes the development of a public bike system initiated by a civic organization that treats participation as a core principle. The analysis shows that the satisfaction of the goals pursued through the adoption of participative principles ...
Philippe Gauthier
doaj  

Responsible Conduct: The Ethics of It All in Life and Research [PDF]

open access: yes, 2013
The teaching and learning of ethics as applied generally to the human condition as well as specifically to ethics in research are explored in this discourse.
Lumpkin, Angela, Stoll, Sharon K
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Sermons In Stones. Argument And Artefact For Sustainability

open access: yesLes Ateliers de l’Ethique, 2010
The focus of the study is on the values, priorities and arguments needed to advance ‘design for sustainability’. The discussion critiques conventions related to innovation and technology and offers a product design approach that emphasises minimal ...
Stuart Walker
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Développement durable : Quelques points litigieux [PDF]

open access: yesLes Ateliers de l’Ethique, 2006
Sustainable development aims to reconcile various, if not antagonistic, necessities: the economic, the social,and the environmental necessities. One may thus ask oneself whether it really answers the fundamental intuitions of the ecological conscience ...
Catherine Larrère
doaj  

Applied Ethics and Applying Ethics

open access: yes, 2013
Poster for the workshop "Applied Ethics and Applying Ethics" organized by the Centre for Advanced Study in Bioethics on 25 to 26 October ...
openaire   +1 more source

Roboethics: Ethics Applied to Robotics [PDF]

open access: yes, 2011
This special issue deals with the emerging debate on robo- ethics, the human ethics ap- plied to robotics. Is a specific ethic applied to robotics truly neces- sary?
Solis, Jorje   +2 more
core  

On the Contribution of Philosophical and Geoscientific Inquiry to Geoethics (qua Applied Ethics) [PDF]

open access: yes, 2017
This paper is about the methodology of geoethics qua applied ethics. In particular, I investigate the contributions of philosophical and geoscientific inquiry. My investigation is based on a general model of geoethical research.
Pölzler, Thomas
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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