Results 71 to 80 of about 7,212,800 (230)

Ethics and collective identity building: Scandinavian semicommunication and the possibilities of Philippine ethics

open access: yesEtikk i Praksis: Nordic Journal of Applied Ethics, 2015
How should national societies build legitimate and inclusive collective identities amidst prolific multiculturalism and linguistic diversity? We argue that cultural ownership of particular ways of framing ethics should be part of this collective identity
Jeremiah Lasquety-Reyes, Allen Alvarez
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Ethics Commission extends financial disclosure filing deadline

open access: yes, 2020
"March 27, 2020."; At head of title: For immediate release; "For more information, contact Paul M. Nick, Executive Director.
Ohio Ethics Commission
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Applied Ethics

open access: yes, 2010
Applied ethics is a branch of ethics devoted to the treatment of moral problems, practices, and policies in personal life, professions, technology, and government. In contrast to traditional ethical theory—concerned with purely theoretical problems such as, for example, the development of a general criterion of rightness—applied ethics takes its point ...
Petersen, Thomas Søbirk; id_orcid 0000-0002-1955-8165   +1 more
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Relevance of clinical ethics support services in specialized outpatient palliative care teams and inpatient hospices

open access: yesBMC Palliative Care
Background and objectives Clinical ethics support services (CES) may support palliative care teams in ethical conflicts. However, it is not known to what extent these services are available, used and how their relevance is perceived by the teams.
Carola Seifart   +4 more
doaj   +1 more source

Interpretation of Values in the Epitaphs on the Tombstones of Old Jewish Cemetery in Bratislava

open access: yesCommunications, 2018
The aim of the paper is to find the most frequent links and connotations of the notions related to the values of the Jewish religious community in Bratislava before WWII.
Jarmila Jurova, Marek Debnar
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Ethics education in applied sport psychology [PDF]

open access: yesFizička Kultura, 2017
In applied sport psychology psychologists are often required to provide their services outside of the framework of traditional clinical practice, which has its advantages and limitations.
Vesković Ana V., Petrović Nikola M.
doaj  

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