Results 21 to 30 of about 416,215 (289)

Applied linguistics [PDF]

, 2017
робоча програма навчальної дисципліниРабочая программа учебной дисциплиныSyllabus of the educational ...
Колесник, Олександр Сергійович
core  

Building ‘applied linguistic historiography’ : rationale, scope and methods [PDF]

, 2015
In this paper I argue for the establishment of ‘Applied Linguistic Historiography’ (ALH), that is, a new domain of enquiry within applied linguistics involving a rigorous, scholarly and self-reflexive approach to historical research.
Smith, Richard
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METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

Applied linguistics, performance theory, and Muhammad Ali's Japanese failure [PDF]

, 2017
One of the more colorful realizations of the age-old striking versus grappling rivalry came in 1976, in a fight billed as boxing versus professional wrestling.
Miracle, Jared
core   +1 more source

Targeting Cystine Metabolism in the Lung Cancer Environment Enhances the Efficacy of Immune Checkpoint Inhibition

Advanced Science, EarlyView.
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu, Shumin Li, Jiaji Wu, Shumin Xu, Mo Shen, Chenyang Wang, Lundqvist Andreas, Jianghao Yu, Zhiyong Xu, Yueli Shi, Nana Liu, Yunke Yang, Jiangnan Zhao, Ying Yang, Pingli Wang, Peng Yi, Jin Cheng, Junhui Sun, Mengshu Li, Peng Xiao, Kai Wang   +20 more
wiley   +1 more source

Guide for conducting research in applied linguistics [PDF]

, 2019
La investigación ha sido una de las áreas más importantes en educación; no solo contribuye a encontrar soluciones a los problemas educativos que surgen en la enseñanza y el aprendizaje, impactando así la realidad del contexto inmediato, sino que también ...
López Londoño, Sebastián, Santacruz Giraldo, Mario Alejandro   +1 more
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Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia‐Induced Stress Granule Formation

Advanced Science, EarlyView.
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li, Zhaojun Liu, Linjie Zhu, Gang Wu, Chen Fu, Hongmin Li, Tong He, Ming Shen, Honglin Liu   +8 more
wiley   +1 more source

Bantu lexical reconstruction [PDF]

, 2016
Lexical reconstruction has been an important enterprise in Bantu historical linguistics since the earliest days of the discipline. In this chapter a historical overview is provided of the principal scholarly contributions to that field of study.
Bastin, Yvonne, Bostoen, Koen
core   +2 more sources

Mesenchymal Stromal Cells Play an Analgesic Role Through a Npy2r Sensory Neuron‐Mediated Lung‐to‐Brain Axis

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang, Taihe Zhou, Yueming Sun, Yuanchen Ma, Yiwen Deng, Keyu Chen, Ruijie Li, Yuan Qiu, Tao Wang, Xiaoyong Chen, Li Huang, Lu Zhu, Xueyi Tu, Ying Wang, Zheming Liu, Rouchen Lin, Yunli Tong, Yuantao Li, Heshe Li, Lin Nie, Rui Fang, Jianqi Feng, Xuhong Wei, Xia Feng, Andy Peng Xiang, Xiaoran Zhang   +25 more
wiley   +1 more source

Decoding Handwriting Trajectories from Intracortical Brain Signals for Brain‐to‐Text Communication

Advanced Science, EarlyView.
By developing a novel framework that optimizes both shape and temporal loss during decoder training, the authors successfully reconstruct human‐recognizable handwriting trajectories from intracortical neural signals for both Chinese characters and English letters, effectively resolving the temporal misalignment problem in clinical BCIs, thereby ...
Guangxiang Xu, Zebin Wang, Kedi Xu, Junming Zhu, Jianmin Zhang, Yueming Wang, Yaoyao Hao   +6 more
wiley   +1 more source