Results 41 to 50 of about 1,651,549 (309)

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Uranyl nitrate crystallizer performance with changing solution level

open access: yesHeliyon, 2019
This manuscript described a dynamic simulation of uranyl nitrate crystallization in a linear crystallizer. Furthermore, a mathematical model of the crystallizer supply system was developed with a related control algorithm; the model contained two piston ...
Igor S. Nadezhdin   +4 more
doaj   +1 more source

Connecting Mathematics and the Applied Science of Energy Conservation [PDF]

open access: yes, 2009
To effectively teach science in the elementary classroom, pre-service K-8 teachers need a basic understanding of the underlying concepts of physics, which demand a strong foundation in mathematics. Unfortunately, the depth of mathematics understanding of
Carbone, R. E., Pearce, J. M.
core   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

Investigation of generalized piezoelectric-thermoelastic problem with nonlocal effect and temperature-dependent properties

open access: yesHeliyon, 2018
In the generalized thermoelasticity with fractional order heat conduction and nonlocal elasticity, a generalized piezoelectric-thermoelastic problem of a both-end-fixed finite length piezoelectric rod with temperature-dependent properties and subjected ...
Danni Li, Tianhu He
doaj   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Exact and explicit traveling wave solutions to two nonlinear evolution equations which describe incompressible viscoelastic Kelvin-Voigt fluid

open access: yesHeliyon, 2018
Two nonlinear evolution equations, namely the Kadomtsev-Petviashvili (KP) equation which describes the dynamics of soliton and nonlinear wave in the field of fluid dynamics, plasma physics and the Oskolkov equation which describes the dynamics of an ...
Md. Mamunur Roshid, Harun-Or Roshid
doaj   +1 more source

A hybrid collocation method for solving highly nonlinear boundary value problems

open access: yesHeliyon, 2020
In this article, a hybrid collocation method for solving highly nonlinear boundary value problems is presented. This hybrid method combines Chebyshev collocation method with Laplace and differential transform methods to obtain approximate solutions of ...
A.O. Adewumi   +3 more
doaj   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

open access: yesFEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Statistical modeling of an integrated boiler for coal fired thermal power plant

open access: yesHeliyon, 2017
The coal fired thermal power plants plays major role in the power production in the world as they are available in abundance. Many of the existing power plants are based on the subcritical technology which can produce power with the efficiency of around ...
Sreepradha Chandrasekharan   +2 more
doaj   +1 more source

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