Results 101 to 110 of about 15,813,200 (328)
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Motor Mechanics Department, 1950s
, 1950 View of original Motor Mechanics Department, in shops in Burwood Road. The premises were acquired in 1927 and had formerly been a drapery and clothing establishment.
Swinburne Technical College
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Discover Mechanical EngineeringThe service life of fatigue-loaded components that already contain manufacturing‑induced microcracks is primarily governed by the direction and the rate of fatigue-crack growth.
S. Krome +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Theoretical and applied fracture mechanics
Theoretical and Applied Fracture Mechanics The Mechanics and Physics of Fracture part encourages publication of original research on Material damage leading to crack growth and/or fatigue.
NOBILE, LUCIO
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Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
PERSPECTIVES IN MECHANICS OF HETEROGENEOUS SOLIDS
, 2011 The Micro- and Nano-mechanics Working Group of the Chinese Society of Theoretical and Applied Mechanics organized a forum to discuss the perspectives, trends, and directions in mechanics of heterogeneous materials in January 2010.
Huang MJ +18 more
core +2 more sources
Editorial Special issue on offshore structure-soil interaction
, 2015 As the offshore industries move from shallow to deep waters in excess of 1000 m, there has been rapid development of ocean engineering practices.
Mark Cassidy, Gao FP(高福平)
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The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Reliability based robust design optimization based on sensitivity and elasticity factors analysis
Journal of Materials and Engineering Structures, 2020 In this paper, a Reliability Based Robust Design Optimization (RBRDO) based on sensitivity and elasticity factors analysis is presented. In the first step, a reliability assessment is performed using the First-and Second Order Reliability Method (FORM)/ (
Naoual KARAR +2 more
doaj