(1) The Boy's Playbook of Science (2) Examples in Applied Electricity (3) Manuale di Fisica ad Uso delle Scuole Secondarie e Superiori [PDF]
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Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
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Applied Science for Metal-Workers. William H. DooleyApplied Science for Wood-Workers. William H. Dooley [PDF]
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Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
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A safe learning environment from the perspective of Laurea University of applied sciences safety, security and risk management students and staff. [PDF]
Savolainen T.
europepmc +1 more source
Some Aspects and Problems of Post-War Science, Pure and Applied* [PDF]
T. E. THORPE
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Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
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Investigating the Design-Science Connection in a multi-week Engineering Design (ED)-based introductory physics laboratory task [PDF]
Reform documents advocate for innovative pedagogical strategies to enhance student learning. A key innovation is the integration of science and engineering practices through Engineering Design (ED)-based physics laboratory tasks, where students tackle engineering design problems by applying physics principles.
arxiv +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
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